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Patent Pick: Nitrone Antioxidants

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Nitrone compounds as personal care antioxidants
WIPO Patent Application WO/2015/134688
Publication date: Sept. 11, 2015
Assignee: Dow Global Technologies LLC

Stronger antioxidants are needed as potential anti-aging ingredients to provide skin protection. One such antioxidant, as disclosed in WO 2012/150370, is resveratrol (3,5,4'-trihydroxy-trans-stilbene). This naturally occurring polyphenolic found in the skin of grapes and other fruits has been investigated for its chemopreventive properties against UV-induced skin damage and ROS-induced damages associated with brain function, heart disease and cancer.

According to this patent, however, natural sources for resveratrol are limited, so it is expensive. In relation, these inventors have found that nitrone compounds are equally effective as radical scavengers at lower concentrations, or exhibit higher efficacy at equal concentrations.


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