Upcycled Mangosteen Peel Shows Antioxidant, Anti-tyrosinase Activity

This study aimed to formulate and evaluate herbal face creams containing standardized mangosteen peel extract.
This study aimed to formulate and evaluate herbal face creams containing standardized mangosteen peel extract.
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A recent study published in Cosmetics found face creams containing standardized upcycled mangosteen peel extract to demonstrate antioxidant and anti-tyrosinase activity.

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Materials and Methods

A peel extract from the waste product of mangosteen (Garcinia mangostana) was chosen to reduce waste corresponding to Sustainable Development Goal (SDG) 12. Formulations were created using the material and natural surfactants and fragrances. The test formulas were evaluated for organoleptic characteristics including rheology, spreadability and pH.

Accelerated stability and freeze-thaw stability studies, and centrifugation tests also were conducted. Further, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging assays were carried out to assess antioxidant effects. A tyrosinase inhibitory assay was conducted to determine the skin-brightening potential of the test formulas.

Results

According to the researchers, the formulated creams appeared light yellowish-brown in color and homogenous, without phase separation. The creams displayed shear-thinning behavior and optimal pH, which would be ideal for topical application. The creams were stable after being subjected to the various stability tests and, as noted, they demonstrated antioxidant and anti-tyrosinase activity.

It was concluded that the mangosteen-based cream could provide a safe and effective alternative to synthetic antioxidant and brightening products. However, it was noted by the researchers that randomized controlled trials should also be conducted to evaluate the anti-aging and pigmentation control effects.

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