From Collagen Production to 190-nm Emulsions: Literature Findings

Skin and Skin Care
Effects of alpha-ketoglutarate: Son et al. report on alpha-ketoglutarate as a key intermediate in the Krebs cycle and as a rate-limiting cofactor of prolyl-4-hydroxylase.1 Alpha-ketoglutarate also has been shown to have a potent effect on increasing the proline pool during collagen production; however, the details underlying its boosting effect on collagen remain unreported.

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