Technically Speaking: From Enzymes to Fragrance Ingredient Testing: A Literature Overview

Exfoliative proteolytic enzymes: Smith et al report on how topical proteolytic enzymes affect epidermal and dermal properties.1 Although proteolytic enzymes have a history of use in skin care products, it is not known whether they simply induce superficial exfoliation or if, with continued use, they can alter epidermal and dermal skin properties. The authors examined whether enhanced exfoliation resulting from treatment with an aspartyl-dependent acid protease improved appearance and, over time, changes in the epidermis and dermis. Test participants applied a serum containing 15% enzymes and a simple moisturizer twice daily for three months. A matched control group applied the same serum without enzyme and moisturizer.

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