Patent Picks—Cinnamon/​Lemongrass/​Lavender Cotton, Honeysuckle, Sunflower and More Preservatives

Patent Picks are compiled by the editors from publicly available sources. This edition features inventions issued in recent months related to preserving cosmetics and personal care formulas.

Moisturizing, color-protecting amino acid preservatives
U.S. Patent 8802065
Publication date: Aug. 12, 2014
Assignee: Ajinomoto Co., Inc.

Disclosed in this patent are aqueous preservative solutions with a high amino acid content that are particularly effective against fungi and have excellent storage stability. When incorporated in a cosmetic, they impart a high moisturizing effect without causing a sticky feel. In addition, they prevent dyed hair from fading. Such solutions can be achieved by incorporating: pyrrolidone carboxylic acid and/or a salt thereof; a basic amino acid and/or a salt thereof; an acidic amino acid and/or a salt thereof; a neutral amino acid and/or a salt thereof; and lactic acid and/or a salt thereof at a specific ratio and pH.

Cinnamon, lemongrass, lavender cotton antimicrobial
U.S. Patent 8784910
Publication date: July 22, 2014
Assignee: Lonza Inc.

The present invention describes an antimicrobial composition comprising an effective amount of a mixture comprising at least two of: a) lemon grass oil; b) cinnamaldehyde, cinnamon oil, Cinnamomum cassia, cinnamon extract, cassia leaf oil, 3,4-dihydroxycinnamic acid or salt thereof, or a mixture thereof; c) sorbic acid or a salt thereof; d) erythorbic acid or a salt thereof; e) benzoic acid or a salt thereof; f) arabinogalactan, galactoarabinan or a mixture thereof; g) a hexahydro-iso-alpha-acid, tetrahydro-iso-alpha-acid or a mixture thereof; h) Achillea fragrantissima (Santolina fragrantissima Forssk., lavender cotton) oil; and i) δ-gluconolactone. The invention also provides a product, preferably other than foodstuff, pharmaceutical or cosmetic, comprising an effective amount of cinnamaldehyde or a mixture of cinnamaldehyde and one or more alkanol-dialkyl hydantoins.

Isothiazolone-containing preservative for microbicidal finishing
U.S. Patent 8765795
Publication date: July 1, 2014
Assignee: Air Liquide Sante

Described herein is a preservative that provides microbicidal finishing. In particular, it comprises: a) one or more isothiazolones with b) one or more 1- or 2-(C1 to C24-alkyl)glycerol ethers (glycerol monoalkyl ethers). According to the inventors, this technology aims to preserve cosmetic and pharmaceutical products via broad-spectrum activity and even at a low use concentrations. It also can be stored for long periods.

Enzymatically modified sunflower oil antimicrobial
WIPO Patent Application WO/2014/097218
Publication date: June 26, 2014
Assignee: Universidade Federal de Minas Gerais – UFMG, and Phoneutria Biotecnologia e Serviços Ltda.

Described by these inventors is an alternative way to overcome the limitations encountered with the use of essential oils as preservatives. A sunflower oil (Helianthus annuus) modified enzymatically by treatment with lipase is proposed, along with a process for its production and the use of derivatives thereof as antimicrobial agents for preserving foodstuffs, cosmetics and drugs.

Xylitol esters and ethers for pharmaceuticals and cosmetics
U.S. Patent 8716506
Publication date: May 6, 2014
Assignee: Chemyunion Quimica Ltda.

This invention applies esters and ethers derived from xylitol, obtained by organic synthesis, as alternative emollients, moisturizers, emulsifiers, co-emulsifiers and preservatives for pharmaceutical, cosmetic and veterinary products. The molecules are mainly xylitol esters and ethers associated to the chains of fatty acids and alcohols, applied isolated or in association with other molecules of known preserving and/or moisturizing/emollient actions such as: phenoxyethanol, butylene glycol, glycerin, caprylyl glycol, ethyl hexyl glycerin, phenetyl alcohol, nisin and lactoferrin, among others. Some embodiments present antimicrobial action against, for example, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Aspergilus niger and Candida albicans.

Glycerol ether and aromatic alcohol for controlling mycobacteria
U.S. Patent 8710103
Publication date: April 29, 2014
Assignee: Air Liquide Sante

The objective of this invention is to provide a disinfectant with activity against mycobacteria that does not irritate the skin and that does not have degreasing activity; i.e., it does not include a high content of lower alcohols such as ethanol or isopropanol. A method to preserve cosmetic products also is described by adding to them a concentrate, which includes: a) 1-(2-ethylhexyl) glycerol ether, and b) one or more aromatic alcohols, whereby a) and b) have a weight ratio less than or equal to 0.15.

Honeysuckle for natural preservation
U.S. Patent 8623430
Publication date: Jan. 7, 2014
Assignee: Woodcliff Skincare Solutions, Inc.

Described in this patent is a cosmetic preservative that comprises Lonerica sp. (honeysuckle) extract, a metal chelating agent and ethanol in amounts effective to inhibit microbial growth including bacteria, molds and yeast. The effectiveness may be enhanced by the addition of a phospholipid, ascorbic acid and ascorbic acid salts. Effectiveness against microbial growth is further improved by addition of a combination of 1,2-hexanediol, 1,2 octanediol and tropolone. Specific formulations are provided.

Organic carboxylic acid to preserve skin care
U.S. Patent 8580861
Publication date: Nov. 12, 2013
Assignee: Pibed Ltd.

The present invention discloses preservative compositions suitable for replacing, partially or in totality, conventional preservatives in skin care and hygiene cosmetic or pharmaceutical products. The formulations include an organic carboxylic acid present in a concentration from 0.01% to 30% w/w, and an alcohol present at 0.01% to 60% w/w. The formulations also include an inorganic salt from 0.01% to 80% w/w and a chelating agent at 0.01% to 20% w/w.

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