Researchers have uncovered a key role of commensal skin microbiota in the wound healing process, according to a new study published in Nature Immunology.
Here, scientists show that commensal bacteria colonizing skin wounds trigger the activation of neutrophils. This initiates a cascade (detailed in the article abstract) that ultimately produces type I interferon (IFN).
IFN accelerates wound closure by triggering skin inflammation and early, T cell-independent wound repair responses. These produce major growth factors required for healing.
For more information, see the article abstract.