Croda has launched four excipients to improve and maintain the solubility and stability of actives in solutions and formulations, and ensure optimal oral delivery.
See also: Wellness and Nutricosmetics; Free Ebook
The ingredients include: Super Refined GMCC (Glyceryl Monocaprylocaprate), Super Refined L18POG (Linoleoyl PEG-6 Glycerides), Super Refined PGML (Proplene Glycol Monolaurate) and Super Refined O18POG (Oleoyl PEG-6 Glycerides). They are offered as primary surfactants within the company's Oral Lipid Delivery platform.
According to the company, this platform aims to meet the challenges of orally delivering active pharmaceutical ingredients (APIs), in particular. The self-emulsifying and self-microemulsifying drug delivery systems (SEDDS and SMEDDS) are said to improve oral bioavailability; to ease manufacturing and scale-up; to reduce inter/intra subject variability and food effects; to deliver peptides; to lessen the influence of lipid digestion; and to increase loading capacity. They also have an exceptionally low impurity profile, which helps to improve stability and shelf life.