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Deinde Unveils Radiance-Restoring Overnight Mask for a Morning Glow-Up

Deinde harnesses breakthrough biotechnology to support skin longevity at the cellular level.
Deinde harnesses breakthrough biotechnology to support skin longevity at the cellular level.
Deinde

DEINDE is positioning its Radiance-Restoring Overnight Mask alongside its Overnight-Sculpting Face Tape as a complementary, performance-driven system designed to optimize overnight skin recovery.DEINDE is positioning its Radiance-Restoring Overnight Mask alongside its Overnight-Sculpting Face Tape as a complementary, performance-driven system designed to optimize overnight skin recovery. DeindeDeinde has announced its latest and greatest product launch: the Radiance-Restoring Overnight Mask, a silky, lightweight treatment balm that transforms dry, fatigued skin overnight, per the company. 

Clinically proven to improve skin texture, tone and brightness, this deeply moisturizing formula is said to melt effortlessly into the skin, delivering visible radiance by morning.

DEINDE is positioning its Radiance-Restoring Overnight Mask alongside its Overnight-Sculpting Face Tape as a complementary, performance-driven system designed to optimize overnight skin recovery. 

The medical-grade kinesiology tape is engineered to work in tandem with the mask to support wrinkle-smoothing outcomes while promoting more efficient absorption of active ingredients during sleep. 

By leveraging mechanical support rather than injectables or neurotoxins, the pairing reflects a growing executive focus on non-invasive, at-home solutions that enhance treatment efficacy and deliver visible results by morning.

Science Behind the Glow

Deinde New Overnight MaskImage courtesy of DeindeThe Radiance-Restoring Overnight Mask is powered by advanced biotechnology and a blend of clinically proven ingredients:

  • 10% Gluconolactone: A gentle yet effective polyhydroxy acid (PHA) that exfoliates dead skin cells, smooths rough texture and promotes healthy cell turnover for a radiant, even complexion.
  • Biotech-derived naringenin: Deinde’s patented polyphenol clinically proven to reduce skin aging markers by 96%. It combats inflammaging by strengthening the skin’s resilience against environmental stressors while maintaining moisture and elasticity.
  • Biotech-derived squalane: A bio-identical lipid that locks in hydration, leaving skin softer, smoother, and more balanced.
  • Glycerin: A powerful humectant that draws in moisture to hydrate, soften and plump the skin.

Clinically Proven Results

In clinical testing, 30 subjects who used the product 2x daily for 8 weeks experienced significant results:

  • 100% of participants reported significant improvement in skin moisture.
  • 84% saw improvement in skin tone.
  • 81% noticed smoother skin texture.

Additionally:

  • 100% said their skin felt hydrated.
  • 91% reported smoother skin texture.
  • 91% observed improved radiance.

Biotech Meets Skin Care Innovation

Deinde harnesses breakthrough biotechnology to support skin longevity at the cellular level. As previously reported, Deinde is backed by biotech company Debut, which uses fermentation and cell-free biotech to scale up the manufacture of bioactives such as naringenin — which are typically found in only trace amounts in the nature. 

Backed by Debut’s team of over 80 scientists and more than $100 million in research and development, Deinde uses AI-driven screening to analyze over 50 billion molecules, rapidly identifying those with the most potent skin care potential. These materials can reportedly be manufactured and incorporated into finished products in as little as six weeks.

This advanced discovery engine enables Deinde to deliver next-generation formulations that combine pharmaceutical-grade efficacy with clean, conscious beauty.

Sustainable and Dermatologist-Tested

Deinde's products are also dermatologist-tested, vegan, cruelty-free and designed for all skin types, including sensitive or allergen-prone. The Radiance-Restoring Overnight Mask is fragrance-free, soy-free and gluten-free. 

In addition, with sustainability at the core of Deinde’s mission, all product components are made from post-consumer recycled (PCR) materials and are fully recyclable.

Q&A: Joshua Britton, CEO of DEINDE

Targeting Inflammaging for Resilient, Revitalized Skin

'Our R&D philosophy focuses on identifying ingredients that precisely target key biological processes in the skin to support skin longevity,' says Joshua Britton, CEO of Deinde."Our R&D philosophy focuses on identifying ingredients that precisely target key biological processes in the skin to support skin longevity," says Joshua Britton, CEO of Deinde.DeindeBritton: Our R&D philosophy focuses on identifying ingredients that precisely target key biological processes in the skin to support skin longevity. With this approach, we identified a clear opportunity to develop an overnight mask that works in harmony with the skin’s natural regenerative cycle during sleep to halt inflammaging , the chronic, low-grade inflammation that puts stress on our cells, and ultimately delays future signs of aging.

DEINDE Radiance-Restoring Overnight Mask is powered by our patented biotech Naringenin which is 15X more powerful than niacinamide at interrupting inflammaging to help strengthen skin resilience and restore elasticity, with results further enhanced by consistent, healthy sleep habits. 10% gluconolactone, a gentle PHA, works overnight to promote healthy cell turnover and refine rough texture while preserving the skin barrier. 

Biotech squalane and glycerin provide sustained hydration during sleep, leaving skin supple, bouncy, and visibly revitalized by morning. Designed for the savvy beauty consumer who values multitasking products designed for performance and an optimized routine, this overnight treatment delivers powerful results by deeply penetrating the skin and allowing the biotech active to absorb over an extended period, enhancing sleep’s regenerative cycle, and making it a natural, strategic addition to the DEINDE portfolio.

AI-Powered Ingredient Discovery

Britton: Backed by cutting-edge biotech and AI company, Debut, DEINDE harnesses Debut’s proprietary BeautyORB platform, an advanced AI discovery engine powered by over 580 million genetic data points capable of screening 96 billion ingredients against specific skin target claims.

DEINDE uncovers new, breakthrough ingredients that target consumer skin concerns at the cellular level, transforming traditional restorative, “anti-aging” claims into scientifically proven benefits for long-term skin health and longevity.

As consumer behavior shifts to a more preventative approach to beauty, DEINDE creates products designed to delay future signs of aging. By moving beyond legacy actives as hero ingredients, DEINDE delivers clinically proven, personalized, next-generation ingredients and formulas developed to the highest safety standards, bridging the gap between pharmaceutical-grade efficacy and modern clean beauty.

Bridging Performance-Based Biotech and Sensorial Beauty Innovation

Britton: DEINDE’s clinicals are best-in-class and instrumentation-based to provide objective, precise measurements of key skin benefits . We invest the money to go beyond perception-based clinicals to ensure results are performance-based  and inclusive of unique skin types.

While some brands may rely solely on their science to “speak for itself,” at DEINDE, we take things a step further by obsessing over perfecting textures that are truly addictive. We combine irresistible formulas and thoughtfully designed packaging to elevate each product into a sensorial, vanity-worthy experience.

Every DEINDE product is designed with a TikTok-first mindset, guided by three core questions:

  1. Does the formula’s hero ingredient and key benefit immediately stand out and capture modern consumer attention?
  2. Is the texture richly sensorial, reflecting K-beauty-inspired innovation that consumers crave?
  3. Is the packaging visually arresting—e.g truly “thumb-stopping”?

DEINDE's Radiance-Restoring Overnight Mask delivers across all three, ticking every box for the highly visual, modern beauty consumer.

To further elevate our consumer experience, DEINDE is committed to making biotech innovation accessible. While many brands raised MSRPs at the start of 2025, DEINDE reduced prices on our hero SKUs, made possible by scaling production of our proprietary biotech Naringenin to generate manufacturing efficiencies. The cost savings were passed on to our consumers, reinforcing our belief that breakthrough science should be within reach.

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