Lubrizol Life Science introduces Curcushine microcapsules, bioavailable microencapsulated curcumin for the “beauty-from-within” market. Specifically, the microcapsules aid in anti-aging, UV protection and hair care.
Curcumin has been shown to delay skin aging by protecting the skin's structures and proteins, including collagen and elastin from oxidative and inflammatory damage. The antioxidant properties of curcumin can reduce ROS in cells and eliminate the effects of Advanced Glycation End-products (AGEs) on the divergent regulation of gene expression of receptors.
The delivery system transforms the curcumin into a bioavailable formulation using a natural encapsulant matrix that protects and embeds the curcumin. The increased bioavailability of Curcushine microcapsules can be attributed to the solubility in water due to the small dimension of the particles. The high solubility characteristic also allows easy incorporation of the product into varieties of nutricosmetics and beauty drinks.
In an in vitro study from Lubrizol showing the ROS reduction effect of Curcushine, the microcapsule was shown to have significant protection from oxidative stress on HDFa cell structures. Curcushine was also shown to exhibit better antioxidant performance compared to other extracts, thus preventing aging.
When studying water solubility, Curcushine exemplified better water dispersion compared to free curcumin extract.
In an in vitro study, Curcumin was shown to protect from UVA-induced glycation by decreasing AGEs up to 63.7%, compared to the untreated control. In another in vitro test with the company, Curcushine’s bioavailability is much higher than the control, lasting 8 hr after intake. The microcapsules displayed a pharmacokinetic profile of slow release of curcumin compared to the quick absorption, metabolization and removal of free curcumin.
The formulation is gluten-free, vegan, plant-based, and kosher- and halal-certified.
For more information, contact Lubrizol Life Science.