Sederma has developed a novel ingredient to sustain and optimize hyaluronic acid turnover in the skin. Optim Hyal (INCI: Not Provided) contains the company's Glycokines—specific signaling oligosaccharides that structurally and functionally mimic the hyaluronic fragments found in the skin. These oligosaccharides have been found to stimulate hyaluronic acid synthesis both in keratinocytes by 40%, and fibroblasts by +35%, for visible improvement in skin smoothness. Main wrinkle density was reduced from 46% up to 96%, and moisture and suppleness were improved in one month. This ingredient also complies with Chinese cosmetic ingredient regulations.