Ichimaru Pharcos recently launched PeoGlow, a natural active ingredient derived from peony root designed to address skin tone unevenness linked to the glycation process — specifically the interaction between Advanced Glycation End Products (AGEs) and their receptors (RAGE).
Targeting the Glycation Cascade
According to the company, PeoGlow (INCI: Butylene Glycol (and) Water (Aqua) (and) Paeonia Albiflora Root Extract) represents a breakthrough in skin tone care by targeting the glycation domino run — a chain reaction where AGEs bind to RAGE, triggering hyperpigmentation (brown), darkening (black) and dullness (gray).
This mechanism is now understood to be a root cause of uneven skin tone, affecting both melanocytes and keratinocytes, per the company.
Key Claims and Benefits
Key product claims and benefits supported by the ingredient include the following.
- Inhibits AGEs-RAGE interaction
- Reduces AGEs-related brown pigmentation
- Disrupts AGEs-RAGE signaling associated with black and gray tone
- Improves overall skin tone uniformity
Applicable across facial and body care, PeoGlow is said to be ideal for skin brightening, anti-aging, under-eye treatments, hand creams and body creams.
Technical Details
Additional formulating considerations are:
- Form: Yellowish brown to brown liquid with a characteristic odor
- Recommended dosage: 1%
- Safety: Toxicity and safety data available
- Regulatory: JSQI approved, Chinese IECIC 2021 listed, halal certified
- Patent: Pending in Japan
With PeoGlow, Ichimaru Pharcos aims to offer a scientifically backed approach to correcting brown, black and gray discoloration for a clearer, more even-toned complexion.
