Alleviating Redness with Tetrapeptide-14

Grant Industries Inc. has launched a product that can be used to alleviate skin redness. Granactive AR-1423 (INCI: Water (aqua) (and) Butylene Glycol (and) Camellia sinensis (Tea) Extract (and) Aspalathus linearis (Rooibus) Extract (and) Boswellia serrata Extract (and) Honey Extract (and) Tetrapeptide-14 (and) Phenoxyethanol (and) Sodium Benzoate) can be used in cosmetic treatments to alleviate the redness associated with red (rosacea-like) skin types or after mild sun exposure.

According to the company, this ingredient combines a redness diminishing peptide with the antioxidant properties of tea, the calming properties of Boswellia serrata, and the soothing quality of honey. Tetrapeptide-14, a specific peptide sequence designed by the company's supply partner Helix Biomedix, acts by down regulating interleukin-6 (IL-6) to prevent inflammation, which in turn reduces MMP-1 damage with the net effect of a bright and even skin appearance.

The ingredient was screened in a leave-on cosmetic treatment at 5% on several subjects with excessive facial redness and, when used with tetrapeptide-14 and botanicals, reportedly diminished the redness by 50% in 4 weeks.

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