IBR Ltd. created an aqueous extract of Asteriscus Graveolens to shield the skin from pollution damage. IBR-Pristinizer 1601 (INCI: Water (aqua) (and) AsteriscusGraveolens Flower/Fruit/Leaf/Stem Extract) was shown to have antioxidant, anti-inflammatory and detoxification benefits.
Constant exposure to environmental toxins leads to accumulated DNA damage and chronic inflammation, both leading to premature aging. The extract assists protecting cells from air pollution-induced oxidative stress by reducing the expression of genes leading to an increased protein accumulation of the antioxidant master regulator. It protects cells from the inflammatory response following exposure to air pollution by reducing the expression of genes leading to an attenuated cytokine secretion and thereby inflammation.
Finally, it protects cells from air pollution-induced cell death by reducing the expression of cell death-related genes and stimulating expression of phase I enzymes such as cytochrome p450, thereby detoxifying hazards and increasing cell survival. It is recommend at 1-3% in skin care formulations.