Research currently at press with the Journal of Molecular Liquids describes a simple and effective technique to accurately predict the water concentration in natural deep eutectic solvents (NaDES).
According to the authors, NaDES are renewable and biodegradable solvents with a wide range of applications. They can be used as solvents to derive natural plant extracts, in biocatalysis or for nanparticle synthesis.
The water content in these solutions is critical to their properties. For this reason, the authors sought to estimate its proportion in NaDES. They employed a technique coupling Attenuated Total Reflectance-infrared spectroscopy (ATR-IR) to multivariate methods and found it could accurate predict the water content without the need for labeling or sample preparation.
The authors note this preliminary work supports the identification and creation of easily accessible analytical tools to further the development of green chemistry solvents.