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Recent in Testing (page 29 of 33)
May 6, 2013 | Timothy Gao, PhD; Peter Landa; Regan Tillou; and Kevin Gallagher, Croda Inc.
To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.
May 6, 2013 | Anthony J. Ribaudo, Textile Research Institute (TRI) Princeton
Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.
May 6, 2013 | Trefor Evans, PhD, TA Evans LLC
It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.
May 1, 2013 | P. Ziosi, S. Manfredini, S. Vertuani, V. Ruscetta, M. Radice and G. Sacchetti, Università Degli Studi di Ferrara; and R. Bruni, Università Degli Studi di Parma
In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.
May 1, 2013 | Leigh A. Belcher, Carl F. Muska, PhD, and Joseph W. DeSalvo, DuPont
In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).
Apr 24, 2013 | Sara Farahmand, PhD, University of Cincinnati College of Pharmacy; and Howard I. Maibach, MD, PhD, University of California School of Medicine
While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.
Apr 19, 2013 | Katie Schaefer, Cosmetics & Toiletries magazine
The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.
Apr 19, 2013 | Ali Alikhan, MD, and Howard I. Maibach, MD
In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.
Apr 17, 2013 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California San Francisco
New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.
Apr 16, 2013
Researchers from the University of Aveiro, the University of Coimbra and the University Hospital of Coimbra have developed a dendritic cell-based test for skin sensitizers that can serve as an alternative to animal testing.
Apr 9, 2013
Beiersdorf has created a new method of skin analysis to help it develop new skin care products.
Apr 4, 2013 | Konstantin Tsinman, PhD, Pion Inc.; Bálint Sinkó, PhD, SinkoLAB Scientific Bt.
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.