Most Popular in Testing
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Recent in Testing (page 22 of 34)
Apr 23, 2014 | Paul Cornwell, PhD, and Jeremy Goodwin, PhD, PZ Cussons (UK) Ltd.
This article reviews the mechanisms underlying skin irritation and sensitization, and methods used in a case study to test cosmetic products for their potential to cause irritation. It also covers the main skin conditions that can influence susceptibility to irritation, as well as ingredients affecting the mildness of cosmetic products.
Apr 23, 2014 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California School of Medicine
The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.
Apr 23, 2014 | Hongbo Zhai, MD; Howard I. Maibach, MD; and Heidi P. Chan, MD; University of California San Franciso, Department of Dermatology
While scalp irritation also can be caused by contact with physical or biological agents, this column will discuss the irritation resulting from hair chemicals. The desire for a specific hairstyle or color can render the scalp exposed to different hair chemicals that may result to scalp irritation.
Apr 23, 2014
Researchers from the Drexel University College of Medicine have established a clearer relationship between Staphylococci bacteria and the conditions atopic dermatitis (AD) and eczema.
Apr 23, 2014 | Qing Huang, Zhen-Wu Mei, Koji Takata and Jianzhong Yang, Beauty & Health Innovation Co., Ltd.
The most common approach to determine ingredient deposition on hair is to analyze the treated tresses, but this poses several challenges. Instead, the authors describe a novel approach based on determining the amount of ingredient collected in the rinse water, and back-calculating the amount deposited on hair. Development and validation efforts discussed here use polydimethylsiloxane as a model compound.
Apr 23, 2014 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California at San Francisco School of Medicine
Described here was an in vivo model to determine antioxidative capacity of a topical skin care emulsion versus the emulsion’s vehicle on human skin that was exposed to UVR. Results suggest the test emulsion and its vehicle control inhibited the induction of erythema and reduced inflammation caused by the UV exposure.
Apr 23, 2014 | Marc Pissavini, PhD, Adeline Baud, Stéphanie Marguerie, Karine Desseille and Olivier Doucet, PhD, Coty-Lancaster
The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.
Apr 23, 2014 | Howard I. Maibach, MD, University of California School of Medicine; and Nicolas Atrux-Tallau, PhD, ESPCI ParisTech
Glycerol is one humectant commonly employed due to its high hygroscopic and hyperosmotic properties. It is used in cosmetics as a moisturizer and in pharmaceutical formulations as an active compound. Being naturally present in the skin, glycerol was quickly identified for its role in skin hydration, similar to natural moisturizing factors (NMF).
Apr 23, 2014 | Wolf Eisfeld and Rolf Wachter, Cognis Deutschland GmbH & Co. KG, Florian Schaefer and Wolfram Boucsein, Institute for Physiological Psychology, University of Wuppertal
Pulse volume amplitude, skin conductivity, facial muscle activity and other psycho-physiological parameters can give an objective emotional assessment of consumer response to personal care products, enabling substantiation of claims for wellness effects, as demonstrated here in the setting of cosmetics and fabric care.
Apr 22, 2014 | Rachel L. Grabenhofer, Cosmetics & Toiletries
The industry reacts to a new study published in Contact Dermatitis reviews reports of the UV absorber octocrylene for its potential to cause photo contact allergy.
Apr 21, 2014 | Olga Freis, PhD, Gilles Perie and Andreas Rathjens, BASF Beauty Creations/Care Solutions, Pulnoy and Essey-lès-Nancy, France
The aim of this study was to monitor the evolution of biomechanical and optical properties of the skin with aging. Different biophysical parameters were measured, including skin: elasticity and firmness, color, brightness, fluorescence emission, sebum content, hydration and pH. A significant evolution of the evaluated parameters with aging was observed.
Apr 21, 2014 | Nadine Bresciani, Valérie Poulet and Nathalie Collard, Anemcoli, Lille, France; Raphaél Dugue, Laboratoire Midac, Loos, France
The authors propose an approach to assess the microbial stability of a product during use, referred to as the Microbiological Use Test (MUT), and apply this analysis in case studies to predict the microbiological risk of commercial products. The described test has been used successfully in the development of cosmetics.