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Recent in Testing (page 22 of 34)

Designing Mild Personal Care Products: A Case Study

This article reviews the mechanisms underlying skin irritation and sensitization, and methods used in a case study to test cosmetic products for their potential to cause irritation. It also covers the main skin conditions that can influence susceptibility to irritation, as well as ingredients affecting the mildness of cosmetic products.

Tape Stripping Method in Humans: Comparison of Evaporimetric Methods

The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.

Scalp Irritation From Hair Care Chemicals

While scalp irritation also can be caused by contact with physical or biological agents, this column will discuss the irritation resulting from hair chemicals. The desire for a specific hairstyle or color can render the scalp exposed to different hair chemicals that may result to scalp irritation.

Researchers Dig Deeper Into Relationship Between Bacteria and Atopic Dermatitis

Researchers from the Drexel University College of Medicine have established a clearer relationship between Staphylococci bacteria and the conditions atopic dermatitis (AD) and eczema.

Analyzing Deposition from Rinse-off Hair Products

The most common approach to determine ingredient deposition on hair is to analyze the treated tresses, but this poses several challenges. Instead, the authors describe a novel approach based on determining the amount of ingredient collected in the rinse water, and back-calculating the amount deposited on hair. Development and validation efforts discussed here use polydimethylsiloxane as a model compound.

A Dermatological View: Antioxidant Inhibits UV Erythema In Vivo in Humans

Described here was an in vivo model to determine antioxidative capacity of a topical skin care emulsion versus the emulsion’s vehicle on human skin that was exposed to UVR. Results suggest the test emulsion and its vehicle control inhibited the induction of erythema and reduced inflammation caused by the UV exposure.

Method to Reproduce In vitro Cosmetic Product Photostability Findings

The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.

The Effect of Glycerol on the Water-holding Capacity of Chemically Irritated Skin*

Glycerol is one humectant commonly employed due to its high hygroscopic and hyperosmotic properties. It is used in cosmetics as a moisturizer and in pharmaceutical formulations as an active compound. Being naturally present in the skin, glycerol was quickly identified for its role in skin hydration, similar to natural moisturizing factors (NMF).

Objective Emotional Assessment of Perceivable Wellness Effects

Pulse volume amplitude, skin conductivity, facial muscle activity and other psycho-physiological parameters can give an objective emotional assessment of consumer response to personal care products, enabling substantiation of claims for wellness effects, as demonstrated here in the setting of cosmetics and fabric care.

Octocrylene Concerns Flag Industry's Attention

The industry reacts to a new study published in Contact Dermatitis reviews reports of the UV absorber octocrylene for its potential to cause photo contact allergy.

Correlating Aging with Skin’s Mechanical and Optical Properties

The aim of this study was to monitor the evolution of biomechanical and optical properties of the skin with aging. Different biophysical parameters were measured, including skin: elasticity and firmness, color, brightness, fluorescence emission, sebum content, hydration and pH. A significant evolution of the evaluated parameters with aging was observed.

Proposed Method to Evaluate the Microbiological Stability of Cosmetics During Use

The authors propose an approach to assess the microbial stability of a product during use, referred to as the Microbiological Use Test (MUT), and apply this analysis in case studies to predict the microbiological risk of commercial products. The described test has been used successfully in the development of cosmetics.

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