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Section: Testing > Microbiology

Microflora850

Natural vs. Synthetic Antimicrobials and HDAC as an Indicator of Microflora Health

This article reviews the role of skin microflora in protecting skin, and assesses how the histone deacetylase (HDAC) enzyme is implicated. From this, HDAC expression is used as an indicator to compare the effects of traditional biocides and preservatives with natural antimicrobials on skin’s microbiome. Results suggest the latter effectively preserve products while maintaining a healthy microbiome.

In the case of fluctuating PET results for w/o products, it can be useful to increase the number of samples to verify the results.

Determining Preservative Efficacy in W/O Formulas, Part II: Making Microbiological Safety Assessments

The relevance of microbiological tests for w/o formulas has been questioned, mandating a more holistic approach. This second article in a series examines the failure rate of PETs for w/o products but looks at why this does not mean insufficient stability.

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Mitigating 'Maskne:' Boldo to Balance Sebum, Bacteria and Redness in Acneic Skin

Peumus boldus (boldo) extract was tested for effects on sebum production, S. aureus growth and C. acnes lipase activity in vitro, as well as on skin redness in vivo. This work aimed to develop a natural ingredient to control sebum, inhibit microbes and their activity, and reduce redness in acne-αfflicted skin.

Microbiological test methods for w/o formulas have raised questions in terms of their suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods and options for their optimization. It also critically observes to what extent test results provide relevant information for an appropriate safety assessment. Part II, in August 2022, will explore a holistic approach to more accurately assess microbiological safety.

Determining Preservative Efficacy in W/O Formulas, Part I: Test Performance and Limitations

Microbiological test methods for w/o formulas have raised questions in terms of suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods.

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Assessing the Effects of Blue Light on the Skin in New Validated Method

Studies have shown blue light can have damaging effects on the skin. Genemarkers has developed a reproducible in vitro method for measuring blue light effects. Learn how Genemarkers’ blue light testing can aid product development.

Fluorescent Lab Petri Dish Testing Concep Adobe Stock 1429444187

Testing Innovators: Submit Now to Take Center Stage at the 2026 C&T Allē Awards

Do your methods and devices put cosmetic innovations to the test? The Cosmetics & Toiletries 2026 Allē Awards want to recognize you - enter now.

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