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248 Results
Section: Testing > Method/Process
Methods/Tools
Micropatterning Plus High Content Assay for Skin Research, Explained in Brief
What can high content screening, combined with micropatterning, tell researchers about the efficacy of a cosmetic active? Better yet, what are these techniques? Here, Luc Selig, Ph.D., CEO of CYTOO, explains.
Method/Process
Three Decades of Patch Testing: Trends in the North American Populace
This report evaluates the trends in the results of patch testing. The patch test reactions were surveyed retrospectively. The results were statistically compared between 1970 and 2002 because appropriate interpretation of the numbers has public health opportunities.
Method/Process
Color Electron Microscopy to Blaze a New Trail in Cellular Imaging
A thesis paper from the University of Groningen describes a technique to collect additional data from electron microscopy to create a false color overlay that visualizes and identifies how human cells degrade, organize cargo and more.
SPF/Sun
[podcast] Sunscreen Innovation Act Update: MUsT Test and Penetration Potential
"What’s changed with respect to sunscreen evaluation is ... the test model they are using now is designed for drugs ...and has never been applied previously for the sunscreens," Epstein reports.
Method/Process
P&G Presents 'Omics' Findings in Acne, Male Grooming, Dandruff and Anti-aging
During the World Congress of Dermatology, Procter & Gamble Beauty and Grooming is presenting new findings in acne, male grooming, dandruff and anti-aging based on a broader "omics"—i.e., genomics, proteomics and metabolomics, research tool.
Preservation
Influence of pH on the Preservative Boosting Effect of Chelating Agents
A system based on phenoxyethanol and ethylhexylglycerin (euxyl® PE 9010) from Schülke & Mayr is described here to boost the efficacy of preservatives. To substantiate its efficacy, the effects of the system were checked at pH levels of both 7.0 and 5.0.
Method/Process
Testing Tactics: In Vitro Methods to Test Materials for UV Protective Capabilities
The methods described in this article highlight some of the markers that can be used to assess the UV protective effects of a test material. All of these markers represent either an index of UV-induced damage to the cell or the cell’s response to the damage.
Preservation
Influence of pH on the Preservative Boosting Effect of Chelating Agents
A system based on phenoxyethanol and ethylhexylglycerin (euxyl® PE 9010) from Schülke & Mayr is described here to boost the efficacy of preservatives. To substantiate its efficacy, the effects of the system were checked at pH levels of both 7.0 and 5.0.
Sun Protection
In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results
Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.
Literature/Data
Kao's New Infant Sebum Testing Protocol Can Flag Atopic Dermatitis, Parkinson's Disease
The move is the start of Kao's expansion into health testing services.
Methods/Tools
Haut.AI Explores AI-Enhanced Fluorescence Photography for Non-Invasive Skin Diagnostics
Haut.AI explores the the benefits of using fluorescence photography to uncover skin issues earlier like acne, hyperpigmentation and photoaging. This would allow skin care experts to track treatment progress more effectively.
Sun Protection
In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results
Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.
Testing
Mitigating 'Maskne:' Boldo to Balance Sebum, Bacteria and Redness in Acneic Skin
Peumus boldus
(boldo) extract was tested for effects on sebum production,
S. aureus
growth and
C. acnes
lipase activity in vitro, as well as on skin redness in vivo. This work aimed to develop a natural ingredient to control sebum, inhibit microbes and their activity, and reduce redness in acne-αfflicted skin.
Method/Process
A Dermatological View—Squamometry: An Early Predictor of Changes in the Skin Barrier
Squamometry is useful in identifying the low or subclinical irritation potential of substances even before any change in the TEWL can be measured.
Method/Process
Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair
The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.
Method/Process
Detecting the Protective Power of a Hair Health Multi-peptide: An Integrated Approach
This work measures the antioxidant potential of a hydrolyzed cicer seed extract, a multi-peptide derived from chickpeas, to protect hair. Advanced methods such as FTIR, DCFH-DA assays, cyclic fatigue and DSC testing are combined for a comprehensive view.
Efficacy
The New Stir in Anti-aging: Small-chain Algal Peptides to Regulate Sulfur
Sulfur regulators such as small chain peptides (SCPs) and sulfide donors are an untapped sector for cosmetic science. The present work explores a natural compound to up-regulate cellular sulfur, affect the cell cycle and reduce signs of aging.
Event Coverage
What Beauty Innovations Qualify for the 2025
C&T Allēs
? What Are the Requirements?
What entries compete in the
C&T Allēs
? From ingredients, blends and prototype/finished formulas, to test methods/tools, devices and digital tech, entries span the cosmetic R&D process. Read on for more and enter now - the deadline is Sept. 13!
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