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Method/Process
Measured Dermal Effect of Applying Retin-A
The research reported here focuses on the dermis because it is the site of the primary water retention molecule, hyaluronic acid (HA) in the skin.
Method/Process
Testing A New Platform for Skin Care Emulsions
The authors describe how to test an ingredient for its potential as a skin care emulsion platform using, as an example, a new starch-based ingredient called hydroxypropyl starch phosphate.
Method/Process
Video Imaging in the Measurement of Makeup Efficacy and Performance
Video imaging techniques add quantitative data about the visual effects of makeup when evaluating efficacy and performance of products such as mascaras, lip colorants, facial foundations and nail enamels.
Method/Process
Testing for Dioxin and Furan Contamination in Triclosan
Each batch of triclosan should be analyzed for trace amounts of 2 3 7 8-tetrachlorodibenzo-p-dioxin and 2 3 7 8-tetrachlorodibenzofuran, which can form as unwanted manufacturing by-products, as shown in triclosan from six commercial Asian sources.
Animal Alternatives
Using Tissue Engineered Skin to Eveluate the Irritation Potential of Skin Care Products
Using tissue engineered skin to evaluate the irritation potential of skin care products.
Method/Process
Correlating Porosity and Tensile Strength of Chemically Modified Hair
This study validates the porosity method against the widely accepted method of tensile strength for determining the hair damage imparted to hair due to cosmetic treatments.
Method/Process
Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics
The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.
Method/Process
Cosmetic Testing in 2000 and Beyond
Changes in cosmetic testing are being driven by regulation and advanced technologies, such as new in vitro methods, molecular combinational chemistry and skin delivery. Part of the Series: From Test to Claim.
Method/Process
Flexabrasion: A Method for Evaluating Hair Strength
Both bending and abrasion should be tested—along with extension—when evaluating hair strength, as the authors show in tests of a new active for increasing the strength of bleached hair.
Method/Process
Evaluating Shine on Hair
Marketing research studies have shown that shine is one of they key benefits that women expect from hair care products, particularly from shampoos and conditioners. This article defines shine in the context of hair care and discusses ways to measure it.
Method/Process
Open Assay Models (Washing) for Evaluating Subclinical Irritant Dermatitis
To avoid the acute irritation and dryness that a sincle occlusive surfactant application (24-h) patch tes4t may cause, and to more realistically approximate actual consumer use, an open assay model was chosen.
Method/Process
Dermagenetics
The advent of the complete transcribing of the human genome will forever alter our perceptions of skin care, medicine and nutrition. This column is edited by Lawrence A. Rheins, PhD.
Method/Process
AMS Revolutionizes Absorption and Metabolism Studies
Quantification of percutaneous penetration and metabolism of skin care ingredients has seemed daunting; however, new technology provides a ready solution for the problematic arena. Accelerator mass spectrometry (AMS) is a new analytical method that measures a biological response better than the existing technique.
Method/Process
ATP Bioluminescence: Detecting Microbial Contamination in Dentifrices
In tests on eight dentifrice formulations, a bioluminescence system based on adenosine triphosphate (ATP) detected tested microorganisms qualitatively within 24-27 hours, compared to 5-7 days required for quantitative detection by standard methods.
Method/Process
CTFA Preservative Challenge and Stability Testing Survey
CTFA conducted a survey in 1999 to determine the consistency of the industry's procedures for preservative and stability testing used by the cosmetic industry.
Method/Process
The Safety Factor in Preservative Efficacy Testing
The authors explain how preservative efficacy testing is done to determine whether a formula is adequately preserved. Product contamination problems are frequently caused by inadequate preservation.
Method/Process
Subjective Skin Condition And Its Association With Objective Skin Measurements
From a group of 302 volunteers, the authors obtained both selfreported Subjective evaluations of skin condition and objective measurements of skin conditions, and then looked for correlations between the subjective and objective skin measures.
Sun Protection
Determination of the In Vitro SPF
A ring test at six European test centers showed that SPF evaluations with good reproducibility and comparability could be obtained by an in vitro protocol measuring either transmittance or erythema-effective irradiance of product samples applied on PMMA plates.
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