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Researcher Develops Probe for Non-invasive Below Skin Imaging

Jannick Rolland, PhD, an optics professor at the University of Rochester in New York, has developed an optical probe equipped with a liquid lens that takes images under the skin’s surface without the use of invasive procedures.

ICCVAM and NICEATM Hold Meeting on Endocrine Disruptor Test Method

ICCVAM and NICEATM will hold a peer review meeting on March 29-30, 2011, for an in vitro test method that determines if chemicals are endocrine disruptors.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

Genomics Take the Cake at the SCC December Meeting

The Society of Cosmetic Chemists (SCC) took innovation down to the genome level in not one but two of the five conference tracks presented Dec. 9–10, 2010, at the Annual Scientific Meeting and Technology Showcase.

ISO Equips Formulators to Identify Low-risk Cosmetic Products

The International Organization for Standardization (ISO) has released an international standard that will assist the cosmetic industry in identifying those products that have a low potential for contamination.

Fluorescence Laser Scanning Confocal Microscopy to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

Paper Posted to Aid Manufacturers with Harmonized Microbial Testing

Microtest Laboratories has posted a white paper on its website to help personal care product manufacturers understand microbial limits testing policies in accordance with the harmonization of the United States Pharmacopeia (USP), European Pharmacopeia (EP) and Japanese Pharmacopeia (JP) requirements.

Stability Testing of Cosmetics: Call for Comments

The Personal Care Products Council is requesting public comments on a new Guideline for Stability Testing of Cosmetics by November 15, 2010.

TRI/Princeton Forms Group to Advance Measurement Techniques

TRI/Princeton announced it has formed a Measurement Service and Claims Support group to expand its personal care product performance and claims support test methods with new measurement techniques.

ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products

Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.

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Influence of pH on the Preservative Boosting Effect of Chelating Agents

A system based on phenoxyethanol and ethylhexylglycerin (euxyl® PE 9010) from Schülke & Mayr is described here to boost the efficacy of preservatives. To substantiate its efficacy, the effects of the system were checked at pH levels of both 7.0 and 5.0.

Patent Picks—Imaging Skin, Simulating Eyelashes, Assaying Immune Response and More

This edition of "Patent Picks" features recently issued patents relevant to advances in testing for cosmetics R&D.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

The VS450 is X-Rite's response to customers in the cosmetics industry that are looking for lab-to-production solutions.

Tools to Predict, Assess and Standardize Successful Color Cosmetics

Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.

Skin Toxicology—The Future May Be Orange

Here, industry expert Johann Wiechers, PhD, discusses the frequent use of percentages by toxicologists to calculate skin penetration. To relate this discussion to modern day events, Wiechers describes the skin penetration of orange paint, used by fans of the Dutch national football team.

TRI/Princeton Offers Hair Benchmarking Study to Share Testing Costs

This benchmarking study allows manufacturers to test hair products for conditioning, anti-breakage strengthening, and anti-static flyaway reduction with shared controls and labor to reduce costs by up to 57%. The company is accepting participants until Aug. 15, 2010.

CeeTox Expands In Vitro Capabilities with Acquisition

CeeTox has acquired assets of ADMETRx Inc. that allow it to expand its range of in vitro service offerings. Specifically, the acquired assets allow CeeTox to increase its existing Absorption, Distribution, Metabolism, Excretion (ADME) capabilities.

Evaluating Essential Oils in Cosmetics: Antioxidant Capacity and Functionality

In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.