
In biology, it is generally well-known the extracellular matrix (ECM) provides structural support to surrounding cells in humans and other animals. It is composed of an interstitial matrix and basement membrane based on proteoglycans such as heparan sulfate, chondroitin sulfate, and keratin sulfate; non-proteoglycan polysaccharides such as hyaluronic acid; and fibers such as collagen and elastin, fibronectin and laminin.