A Review of Anti-Irritants, Part I: Barrier Cream Efficacy on Contact Dermatitis*

Irritant contact dermatitis (ICD) is a common form of irritation that can occur when human skin is exposed to potential irritants such as surfactants, cutting oils, etc.1, 2 Minimizing exposure to such irritants is recommended but often not practical since exposure is unavoidable in some occupations including farming, firefighting, medicine, etc. To counteract or suppress irritation responses in the skin, anti-irritant agents are employed. These ingredients, whether naturally occurring or man-made, used alone or in formulations, possess the capacity to reduce irritation caused by acute and chronic exposure to irritants.3

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