Patent Picks—Transformed Bacteria; Anti-biofilm; Modulating Bacteria Response and More in Probiotics

Patent Picks are taken from publicly available sources and cover recent patents issued, or applied for, in the cosmetics, personal care and relevant peripheral markets. This edition features inventions related to probiotics and skin health.

Transformed bacteria for UV protection and more
WIPO Patent Application WO/2014/025938
Publication date: Feb. 13, 2014
Assignee: Topgenix, Inc.

According to this patent, transformed bacteria are being used in modern biotechnology to produce recombinant proteins and various molecules for food, pharmaceutical and biocatalysis applications. Specific examples include human and animal growth hormones, insulin, interferons, cytokines, etc. Among the bacteria already widely used for industrial purposes are the lactic acid bacteria, which are employed as starter cultures. Described herein are compositions based on a population of transformed bacteria that are formulated for topical application to express a compound of interest for a therapeutic or a cosmetic purpose; in one embodiment, the composition is for UV protection.

Anti-biofilms to restore microbiotic homeostasis
U.S. Patent Application 20140037688
Publication date: Feb. 6, 2014
Assignee: Quorum Innovations, LLC

The present invention provides materials and methods that effectively support the skin's innate immunity and/or disperses pathogenic biofilms to restore normal microbiotic homeostasis. In one embodiment, anti-biofilm compositions are described that incorporate probiotic organisms, anti-microbial honey and other ingredients such as prebiotic compounds, other hive products, green tea derivatives, other plant derivatives, and vitamin D3. Said ingredients may be applied in cosmetic or pharmaceutical compositions.

Probiotic peptide for anti-inflammation
U.S. Patent Application 20140057850
Publication date: Feb. 27, 2014
Assignee: Organobalance GMBH

This patent relates to a probiotic peptide obtained from a microogranism, preferably Lactobacillus, and compositions including it for non-therapeutic use in skin care, particularly as an anti-inflammatory. According to these inventors, this technology addresses a need for compounds or compositions that do not depend on cell cultures requiring special care and handling that may be easily produced in a cost-effective manner. Furthermore, it addresses the need for a compound that displays a low effective dose with respect to its beneficial effects.

Rosmarinic acid for skin and hair
U.S. Patent Application 20140023625
Publication date: Jan. 23, 2014
Assignee: L'Oréal and Nestec S.A.

The present invention discloses compositions of rosmarinic acid or its derivatives incorporating a hydrolytic enzyme, or probiotic microorganisms containing or producing hydrolytic enzymes, to improve the biological effects of rosemary extract for administration to, and improvement of, skin and hair. Cosmetics, nutritionals or pharmaceuticals may incorporate said compositions or a derivative thereof.

Lipotheichoic acid to modulate bacteria immune responses
U.S. Patent Application 20140056927
Publication date: Feb. 27, 2014
Assignee: Nestec S.A.

Disclosed herein are compositions for modulating the immune responses induced by Gram-negative bacteria, potential pathogenic Gram-positive bacteria, and/or their derivatives. Said compositions incorporate lipoteichoic acid derived from lactic acid bacteria as an active ingredient in the manufacture of a medicament; oral or topical product for cosmetic, dermatological or opthalmological applications; and a food or petfood composition for modulating bacterial colonization, immune responses and decreasing the inflammatory processes; among others.

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