Patent Picks—Microencapsulation, Maillard Reaction and Ether Guanidines for Antiperspirants

Chosen biweekly for their relevance to personal care, "Patent Picks" are taken from publicly available sources. This edition features technologies related to antimicrobial, antiperspirant and deodorant applications.

Nα-long chain alkanoyl di basic amino acid alkyl ester salts and glycerol monofatty acid ester antimicrobial combo
US Patent 8193244
Publication date: June 5, 2012
Assignee: Nevada Naturals, Inc.

Disclosed in this patent is the combination of Nα-long chain alkanoyl di basic amino acid alkyl ester salts with glycerol monofatty acid esters, which according to the inventors, results in biocidal synergy and the extension of cidal activity of the di basic amino acid derivative. This technology can be applied in a variety of antimicrobial applications such as oral care, wound care, dermatological care, animal care, and cosmetic applications. The invention provides several advantages not observed by using Nα-long chain alkanoyl di basic amino acid alkyl ester salts alone.

Polypeptides having antimicrobial activity and polynucleotides encoding same
US Patent 8192925
Publication date: June 5, 2012
Assignee: Novozymes Adenium Biotech A/S

This patent describes isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. Thus, the antimicrobial polypeptides of the invention may by useful as disinfectants, e.g., in the treatment of infections in the eye, mouth or skin; in antiperspirants or deodorants; or for cleaning and disinfecting contact lenses and teeth.

Microencapsulated delivery vehicle having an aqueous core
US Patent 8192841
Publication date: June 5, 2012
Assignee: Kimberly-Clark Worldwide, Inc.

The current patent describes microencapsulated delivery vehicles comprising an active agent. The vehicles may be introduced into products such that, upon activation, they provide a functional benefit to a substrate, such as a user's skin. Pharmaceutical and/or therapeutic-type active agents for inclusion in the aqueous core composition include anti-dandruff and antiperspirant agents, anti-virals, anti-fungals, odor-neutralizing materials and deodorants, among others.

Dual aerosol spray outlet
US Patent 8191801
Publication date:June 5, 2012
Assignee: The Procter & Gamble Company

This patent describes a spray head for attachment to an aerosol spray unit containing pressurized product. The spray head has at least two separate outlets, one of which has a non-circular cross-section; and a conduit means and a splitting chamber for diverting the flow to the spray outlets. The conduit attaches to a valve stem of the aerosol spray unit and includes outlet means that are in fluid communication with the splitting chamber, which in turn is in fluid communication with the spray outlets. The aerosol spray unit dispenses cosmetic products such as antiperspirants, deodorants and mixtures thereof comprising antiperspirant active particulates and a carrier, wherein the antiperspirant active particulates are not soluble in the carrier.

W/O aerosol emulsions
Publication date: May 31, 2012
Assignee: Pharmasol Corp. and JD Hammer

Disclosed in this patent are water-in-oil aerosol emulsion compositions and related methods; in particular, aerosol emulsions containing an active agent. In some embodiments, the aerosol emulsion comprises a propellant dissolved in the oil phase and may include a pharmaceutical agent to treat the skin. This agent may be an antimicrobial, i.e., antiviral, antibacterial, antifungal, etc.; an anti-acne agent; a corticosteroid; anti-inflammatory compounds; antipruritic; antiperspirant; antidandruff agent; skin protectant; or sunscreen, among others.

Process for treating perspiration using a carbonyl compound capable of reacting via the Maillard reaction
WIPO Patent Application WO/2012/069310
Publication date: May 31, 2012
Assignee: L'Oreal, D Bernard and O Aubrun

This invention relates to a cosmetic process for treating human perspiration, which consists of applying to human keratin a composition containing, in a cosmetically acceptable support: at least one compound comprising at least one free carbonyl function that is capable of reacting with at least one amine compound via the Maillard reaction, and more particularly with proteins of the horny layer of the skin. The present invention also relates to the cosmetic use, as an agent for treating perspiration.

Concentrated, creamy to solid and dry compositions of an oil-in-water emulsion for producing improved foods in terms of sensory aspects and nutrition physiology
US Patent Application 2120135125
Publication date: May 31, 2012
Inventors: G Muschiolik and KO Paulus

The invention relates to an oil-in-water emulsion, substantially comprising protein, polysaccharide and oil or fat having unique stabilizing properties, which is suited for use as a thickener, suspending agent, coating material, and as an additive to food in the production of a plurality of products. In the sector of health care products, the compositions according to the invention are useful as carriers or vehicles in formulations of pharmaceutical, cosmetic and personal hygiene products. Examples include shampoos and conditioners, sunscreen lotions, lipsticks and eye shadow and the like, and may contain amino acids, peptides, proteins and derivatives thereof; UV-screening substances; sebum-regulating agents; antiperspirants and antioxidants.

Antimicrobial ether guanidines
US Patent Application 2120134948
Publication date: May 31, 2012
Assignee: Evonik Goldschmidt GmbH

The present invention relates to the use of at least one ether guanidine and/or of a salt or hydrate thereof for reducing the growth of microorganisms, and to cosmetic and pharmaceutical formulations comprising them. According to the inventors, surprisingly, it has been found that the ether guanidines have very good antimicrobial properties and can be employed in a very simple manner in cosmetic and/or pharmaceutical preparations. Furthermore, the compounds are distinguished by a selective control of undesired microorganisms, in particular those that colonize the skin. An example antiperspirant spray includes: PEG-40 hydrogenated castor oil, 1.0% w/w; alcohol, 20.0%; betaine, 2.0%; water, 56.3%; ether guanidine, 0.3%; aluminum zirconium tetrachlorohydrate, 20%; and preservative as needed.

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