January's Skin Care Patent Picks


Ericacea extracts for combating skin aging
A major object of the present invention is the provision of bioaffecting active agents which elicit an inhibitory effect on collagenases and, to the extent possible, no appreciable side effects. The inventors disclose that extracts of plants of the Ericacea family can be administered to individuals to combat the signs of aging of the skin, e.g., wrinkles and fine lines, for example by inhibiting the expression of metalloproteases, by inhibiting collagen degradation, or by inhibiting UV-induced skin degradation.

Unilever Home & Personal Care USA, division of Conopco, Inc.
Resorcinol derivatives for skin
Disclosed are 4-substituted cyclo-alkyl methyl resorcinol derivatives as actives in methods and cosmetic compositions for skin lightening.

Coty B.V.
Cosmetic product containing mineral water for remineralizing and rejuvenating the skin
Disclosed is a cosmetic composition that can be used to remineralize human skin and to counteract the effects of aging of skin. The composition contains 0.5–3% water of volcanic origin containing Fe, K, Na, Mg, Ca, Si, P, Se, and Zn in the following amounts: 0.01–0.05; 100–300; 1,000–2,000; 80–200; 50–150; 50–150; 0.01 –0.1; 0.001–0.005 and 0.01–0.03 mg/L, respectively. In addition; the composition optionally contains 0.2–0.8% of an extract from samphire Crithmum maritimum, 0.3–0.9% of the peptide palmitoyl-gly-his-lys and 0.8–1.25% hydrolyzed soy protein. 

Integrated Botanical Technologies LLC
Bioactive botanical cosmetic compositions and processes for their production
The bioactive botanical cosmetic compositions described here are derived from membrane and cell serum fractions of plant cell juice. Methods are described for preparing these compositions for use in various cosmetic formulations and as topical skin cosmetic applications.

Galderma Research & Development
Pharmaceutical/cosmetic compositions comprising novel ligands that activate RAR receptors
Novel ligand compounds that activate retinoic acid receptors (RAR) and have the structural formula given in the patent are suited for formulation into cosmetic compositions or pharmaceutical compositions useful in human or veterinary medicine. Cosmetic applications include body and hair hygiene, especially for treating acne-prone skin. Other suggested cosmetic uses are for promoting regrowth of the hair or for limiting hair loss, for combating the greasy appearance of the skin or the hair, for protection against the harmful aspects of sunlight or for the treatment of physiologically dry skin, and for preventing and/or combating photoinduced or chronological aging. 

E.T. Browne Drug Co., Inc.
Topical cosmetic compositions containing alpha arbutin
Disclosed is a topical tyrosinase-inhibiting combination using alpha arbutin and bearberry extract, in synergism, for the purpose of skin lightening. The active admixture is a dermatological serum comprised of alpha arbutin, octyl stearate and polyolprepolymer-2, introduced onto the human skin in liposome form for ultra-deep penetration. 

7,427,273 J
Japan Natural Laboratory Co., Ltd.
Skin beautification cosmetic system using iontophoresis device, ultrasonic facial stimulator, and cosmetic additive
The inventors describe a skin-beautification cosmetic system comprising an iontophoresis device, an infrared (including far infrared) generator, an ultrasonic vibrator, and a cosmetic composition. The system ensures effective action of moisturizing and whitening cosmetics without causing any problem in the skin. By specifying the type of cosmetic to be used, the system can ensure a more effective beautification action, can improve dry skin and aging skin that adversely affect the female skin, and can decompose and remove melanin. Moisturizing and/or whitening cosmetic components such as hydrophilic gel and ultrafine gel are applied to the face or skin or impregnated in a skin contact member section, following which iontophoresis high frequency vibration is applied to the face or skin for a prescribed period of time using an ultrasonic vibrator with a built-in high ionization iontophoresis device and infrared generator.

Mary Kay Inc.
Treatment and composition for achieving skin anti-aging benefits by corneum protease activation
Novel methods and compositions for treating aged and environmentally damaged skin are disclosed. They provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin; it also induces improvements in the appearance, function, and antiaging properties of the skin.

Ciba Specialty Chemicals Corp.
Use of guaiol for treating the skin
Described are compositions comprising (–)-guaiol, further skin-lightening active substance(s) and, optionally, one or more UVA and/or UVB absorbers for skin lightening and melanogenesis inhibition.

BASF Aktiengesellschaft
Use of crosslinked cationic polymers in skin cosmetic and dermatological preparations
The invention relates to the use of at least one copolymer obtained by a method specified in the patent as an additive for skin cosmetic and dermatological preparations. The method calls for free-radically initiated copolymerization of a monomer mixture (MM) comprising 1–99.99% by weight of at least one monomer (M1) chosen from N-vinylimidazoles and diallylamines optionally in partially or completely quaternized form, and 0.01–10% by weight of at least one monomer (ML) that acts as cross-linker and has at least two ethylenically unsaturated, nonconjugated double bonds. Optionally, MM may also include the following: 0–98.99% by weight of at least one neutral or basic water-soluble monomer (M2) that is different from M1; 0–50% by weight of at least one unsaturated acid or unsaturated anhydride (M3); 0–50% by weight of at least one free-radically copolymerizable monomer (M4) that is different from M1, M2 or M3. Subsequent partial or complete quaternization or protonation of the polymer is required in the case where the M1 is unquaternized or only partially quaternized. 

Cosmetic compositions comprising N-acylamino amides
The invention concerns novel compounds of the N-acylamino-amide family, cosmetic or pharmaceutical compositions contain them, and their use for treating body or face skin aging, whether chronobiologic or light-induced. In particular, these compounds are used to treat skin aging caused by decrease of skin elasticity and/or by collagen degradation in the structure of tissues. 

Dana-Farber Cancer Institute Inc.
Method of attenuating reactions to skin irritants
The present invention is directed to a method of inhibiting CD1d activation by administering a composition containing a moiety that blocks CD1d activation. CD1d is a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. Compositions of the invention are useful for the attenuation of CD1d-restricted immune responses, including treatment of skin disorders due to hyperactive immune responses (e.g., contact hypersensitivity), for systemic administration to attenuate ongoing immune responses, and to provide hypoallergenic cosmetic products including pharmaceutical, cosmetic, and skin care compositions. Preferably, these compositions are in a form intended for topical administration. 

Engelhard Lyon
Use of plant extracts for tinting the skin as a function of its phototype
Disclosed is a method for tinting, for coloring skin, or for increasing the tanned appearance of skin comprising the use of an extract of a plant from the family of Compositae or Asteraceae, preferably an extract of chicory (Cichorium intybus L.). Also disclosed is a method of screening a plant for the manufacture of a cosmetic composition for coloring, particularly for tinting, at least one part of skin.

Galderma Research & Development
Biaromatic compounds which activate PPAR.gamma. type receptors and cosmetic/pharmaceutical compositions comprised thereof
Novel biaromatic compounds having the structural formula given in the patent are formulated into cosmetic compositions or pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism).

E-L Management Corp.
Cosmetic compositions and methods comprising Rhodiola rosea
A cosmetic composition comprising a UV-protective amount of at least one rosavin, preferably present in an extract of Rhodiola rosea in a cosmetically acceptable vehicle, and methods of use thereof, including preventing or reducing the signs of photoaging.

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