Top 10 Trends at IFSCC Barcelona 2023

Computational fluid dynamics to optimize scale up, reducing cost and time
Computational fluid dynamics to optimize scale up, reducing cost and time

IFSCC 2023 took place from Sept. 5-7 in Barcelona, featuring 76 podium presentations and 373 posters chosen from 703 abstract submissions. This year's theme was: "Rethinking Beauty Science." Here are the top trends we saw among the podium presentations.

1. Microbiome

Engineering microbes to augment biologyEngineering microbes to augment biology

-not just rebalancing but deeper biological insights
-aging of the microbiome, driven by the skin's environment
-communication/quorum sensing among entities
-microbiome for skin typing
-molecular output of microbes for targeted therapy (vitamins, antioxidants, etc.)
-microbiome as a sensor/indicator (temperature, ROS, TNF-α)
-species variation with perimenopause (higher Cutibacterium levels) and post-menopause (higher Streptococcus)
-holobiont aging
-microbiome to identify inhibitors

2. Massage, Wellness & Touch

-several posters described touch
-effect of moisturization on perceived touch
-holistic beauty: lymphatic and circulatory systems and their influence on epidermal stem cells
-importance of all five senses together - and the general untapped potential they hold
-greater opportunity for the interactions between all parts of human biology (nervous, circulatory, lymphatic, skeletal, etc.)
-remember that in mind-body-skin interactions, the mind is still the brain and part of the body (what do the senses tell the brain?)

3. Advanced Tech - Analytical and Digital Tools

-full tracks on analytical techniques
-in silico identification of peptides for fibroblast growth factor (new area to watch for future actives)
-the next step from augmented reality (AR) is mixed reality (MR) - example of projection makeup (color cosmetics projected onto the skin and synchronized with movement to try on looks faster and more effectively
-quantum computing to speed formulation optimization
-AI to research skin's proneness to skin conditions, acne, etc.
-how 3D printed facial mask geometry affects hydration of skin
-VR for holistic treatment; e.g., kit of candle, lotion and VR glasses sent to the consumer to integrate and create a paradise escape
-computational fluid dynamics to optimize scale up, reducing cost and time
-AI to map the organization of the stratum corneum in young vs. aged skin
-ex vivo sweat model
-advanced test skin model substrates

4. Sensory Experiences and Emotion

-musical interpretation of skin condition and its integration for wellness and emotion, anti-stress response; future potential for autism and dementia 
-cosmetics and beauty as therapy; beyond just beauty and moving into the health realm
-changes in body odor chemistry in response to emotions
-impact of massage on wellness, stress reduction

5. Delivery Systems

-taurine crystal microneedles
-tannic acid-mediated lipid nanovesicles
-quinoa starch encapsulation
-other vesicles

Holistic beauty: lymphatic and circulatory systems and their influence on epidermal stem cellsHolistic beauty: lymphatic and circulatory systems and their influence on epidermal stem cells

6. Biological Targets

-bigger overall pharma presence this year
-3NT synthesis in skin caused by UV/particulate matter exposure and its reduction to protect skin
-mechanisms of quorum sensing
-SIRTs in skin and cells
-keratinocyte-sebocyte crosstalk by exosomes - regulating these to decrease sebum in oily skin or increase sebum in dry skin
-engineering microbes to augment biology
-skin interactome (exposome, microbiome, genome) to address menopausal deficiencies in skin, improve immunity, address hyperpigmentation
-stem-cell derived exosomes for anti-sagging
-peptides for anti-cellulite
-phages
-a whole track featured senescence

7. Nature/Nature-inspired

-Antarctic photolyase for photoaging/skin cancer prevention
-eco-pigments
-natural low eutectic solvent extraction
-anti-stress Medicago sativa sprout
-crossing technology with nature
-reconnecting with nature - concern for the oceans and climate

8. Advances in Hair

-chemosensing in the hair follicle
-vegetal hair dyes/tannins
-anti-hair loss concepts
-stress in hair follicles
-scalp treatment/anti-hair loss treatment with ginsenoside metabolites
-hair follicle stem cells
-improving hair strength by lipid rich cell membrane complex
-measuring hair breakage in Afro-textured hair
-hair fiber characterization

9. Sustainability

-appeared in many tracks
-zero CO2
-microplastic replacement
-greener chemistry
-circular strategies
-biodegradable film former

10. Sunscreens

-sensory in sunscreens
-safe TiO2 nanoparticles
-mineral sunscreens
-dynamic homogenization of inorganic UV filters

More in Event Coverage