Izayoi (INCI: Rosa Roxburghii Fruit Extract) is a sun care active that acts via a newly identified inflammation pathway—keratinocytes damaged by UVB release denatured U1RNA—which is one damage-associated molecular pattern (DAMP). The surrounding non-damaged keratinocytes recognize such DAMPs and respond by initiating inflammatory reactions leading to signs of skin aging, such as wrinkles, age spots or pigmentation. Izayoi inhibits the inflammation cytokines induced by DAMPs.
For more, head to www.ichimaru.co.jp/english.
Editor's note: The Product Roundup is exclusive to magazine advertisers. The theme for March is anti-inflammation and skin soothing.