Boots recently launched its No7 Future Renew collection including four skin care products shown to reverse the appearance of multiple signs of skin damage. The range contains a novel "super peptide" blend, Pepticology, that is said to harness the skin’s natural repair process and the renewal of more than 50 key proteins in skin cells.
The novelty of this work is that the research team used an AI-approach to identify which peptides are most common in skin and could be synthesized and feasibly penetrate the epidermis...
The blend contains two new patent-pending chemical entities and reportedly represents the biggest cosmetic science innovation in No7’s history. The ingredients were developed after 15 years of research into skin aging and repair with the University of Manchester.
According to a report by The Guardian, the novelty of this work is that the research team used an AI-approach to identify which peptides are most common in skin and could be synthesized and feasibly penetrate the epidermis to deeper skin layers where repair occurs. A process of elimination identified two peptides that appeared particularly promising.
The No7 Future Renew range was extensively tested in a diverse group subjects, including 37 studies and more than 4,200 people, plus two clinical trials and 23 user trials. More than half (51%) of the total testing group had skin of color.
At the heart of the collection is the No7 Future Renew Damage Reversal Serum, clinically proven in a blinded split-face controlled trial to reverse the appearance of multiple signs of skin damage including fine lines, wrinkles, lack of luminosity, dryness, uneven skin tone and loss of firmness. Results showed 97% of women in the clinical study had improvements in the appearance of multiple (three or more) visible signs of skin damage.
Unlike retinoic acid, which can cause tolerance challenges such as skin sensitivity and redness, No7's peptide blend is reportedly highly tolerated, being suitable even for sensitive skin. Patent applications have been submitted and are pending for both the new peptides and the delivery system found within the serum.
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No7’s Head of Science Research, Mike Bell, Ph.D., said: “Skin damage happens throughout our lives and is caused by multiple factors including sun exposure, environmental pollution, stress, sleep, temperature and nutrition. The new peptide blend effectively tricks the skin into thinking that it has been damaged, which leads to renewal of key proteins such as collagen and fibrillin. It therefore supports skin’s natural self-repair mechanisms, targeting signs of cumulative damage both on and under the surface. This is a world-first technology only available from No7. We believe it is going to be a game changer for consumers.”
The peptide technology was presented at three scientific conferences including the American Academy of Dermatology Annual Conference in Louisiana, the British Society for Investigative Dermatology Annual Meeting in Glasgow, and the International Societies for Investigative Dermatology meeting in Tokyo.
Ingredients: Future Renew Serum: Water (Aqua), Dimethicone, Butylene Glycol, Glycerin, Methyl Gluceth-20, Isononyl Isononanoate, Polysilicone-11, Niacinamide, Phenoxyethanol, Acrylates/Beheneth-25 Methacrylate Copolymer, Tocopheryl Acetate, Silica, Panthenol, Polysorbate 20, Caprylyl Glycol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Potassium Hydroxide, Xanthan Gum, Sodium Hyaluronate, Hydrolyzed Rice Protein, Decyl Glucoside, Propylene Glycol, Ethylhexylglycerin, Ascorbyl Glucoside, Propanediol, Pentylene Glycol, Tetrasodium EDTA, Hexylene Glycol, T-butyl Alcohol, Sodium Benzoate, Morus Alba Leaf Extract, Palmitoyl Tetrapeptide-94, Palmitoyl Tetrapeptide-95.