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Section: Testing > Sun Protection
Sun Protection
Interpretation of SPF In vivo Results: Analysis and Statistical Explanation
Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.
Sun Protection
Adapting SPF Testing Methods for Mineral Sunscreen Density
A sunscreen layer’s thickness is critical to its SPF. However, current regulations specify a mass application rate for testing, rather than a volumetric application rate. This significantly underrates the SPF values of mineral sunscreens due to their higher densities since, compared with their relative organic counterparts, thinner films are being tested, as will be shown here.
Sun Protection
UV Transmission Assessment: Influence of Temperature on Substrate Surface
This work evaluates the impact of temperature on test substrate surfaces during the application, spreading and drying steps of the in vitro method to measure ultraviolet (UV) transmission. The authors work in a range of temperatures, between 20°C to 35°C, and demonstrate that controlling temperature is a key parameter and should be strictly controlled to ensure reliability.
Sun Protection
Adjusting Substrate/Product Interfacial Properties to Improve In vivo/In vitro SPF Correlation
This work evaluates the impact of a plasma treatment on test substrates to modify their surface energy, to more closely correlate in vitro SPF measurements with in vivo measurements—without chemically altering the test products. The authors chose the level of plasma modification to use on a substrate based on in vivo values; they explain how to choose it regarding specific formulas in a further paper.
Sun Protection
Adjusting Substrate/Product Interfacial Properties to Improve In vivo/In vitro SPF Correlation
This work evaluates the impact of a plasma treatment on test substrates to modify their surface energy, to more closely correlate in vitro SPF measurements with in vivo measurements—without chemically altering the test products. The authors chose the level of plasma modification to use on a substrate based on in vivo values; they explain how to choose it regarding specific formulas in a further paper.
People
Cosmetics & Toiletries
Adds Coty Sun Care Advisor
Cosmetics & Toiletries
is pleased to welcome Marc Pissavini, PhD, to its prestigious Scientific Advisory Board. Pissavini began his career as an analytical chemist and in 1998, joined the sun research department of Coty-Lancaster in Monaco. Since 2008, he has served as the director of Basic and Applied Research for the company.
Sun Protection
Wise Words From the Bench with Gavin Greenoak
After 25 years in the industry, Gavin Greenoak, managing and scientific director of the Australian Photobiology Testing Facility Pty., Ltd. (APTF), continues to strive for a better understanding of the interaction of light and the human body. Greenoak’s career began in cancer research, which has afforded him unique insight of skin biology and the effects of sun exposure.
Sun Protection
New method to Reproduce In vitro Cosmetic Product Photostability Findings
The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.
SPF/Sun
Science Exposed—What Should the Minimum Recommended SPF Be to Avoid Sunburn?
“Science Exposed” is a new column aimed at digging into industry controversies to strip them down to the scientific facts. Here, sun protection expert Brian Diffey, PhD DSc, critiques the current SPF test method.
Sun Protection
Comparatively Speaking: SPF and Calculated SPF
In order to prepare the industry for the upcoming Sunscreen Symposium, organized by the Florida chapter of the Society of Cosmetic Chemists, industry expert Tony O’Lenick asks Dennis Lott to explain the difference between SPF and calculated SPF. This is the first of two columns on sun protection.
Sun Protection
Interpretation of SPF In vivo Results: Analysis and Statistical Explanation
Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.
Sun Protection
Adapting SPF Testing Methods for Mineral Sunscreen Density
A sunscreen layer’s thickness is critical to its SPF. However, current regulations specify a mass application rate for testing, rather than a volumetric application rate. This significantly underrates the SPF values of mineral sunscreens due to their higher densities since, compared with their relative organic counterparts, thinner films are being tested, as will be shown here.
Sun Protection
Characterizing Roughness: A New Substrate to Measure SPF
Here, the authors describe a variable that affects the results of SPF testing in vitro—the roughness parameter—and investigate this variable using standard and molded poly(methyl methacrylate) (PMMA) substrates. They conclude that use of a molded substrate, along with the described control chart, improves the reproducibility of in vitro SPF test results.
Sun Protection
Cutest Offers UVA Sunscreen Testing
Cutest Systems Ltd has installed a Labsphere UV-2000S sunscreen analyzer at the companies laboratories in Cardiff, Wales.
Sun Protection
Determination of the In Vitro SPF
A ring test at six European test centers showed that SPF evaluations with good reproducibility and comparability could be obtained by an in vitro protocol measuring either transmittance or erythema-effective irradiance of product samples applied on PMMA plates.
Sun Protection
Quantifying Benzophenone-3 and Octyl Methoxycinnamate in Sunscreen Emulsions
The authors have validated a high performance liquid chromatographic (HPLC) method for the quantitative determination of benzophenone- 3 and octyl methoxycinnamate present in sunscreen emulsions.
Sun Protection
Quantifying Sunscreens and Preservatives in Cosmetic Products
The authors propose and validate an HPLC method for simultaneous quantitation of commonly used commercial sunscreen actives and preservatives in cosmetic emulsions.
Sun Protection
ISPE Presents Complete Immersion SPF Testing
ISPE Laboratories presents a new method to evaluate the solar protection factor of water-resistant products.
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