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266 Results
Section: Testing > Method/Process
Method/Process
Influence of Skin Diffuse Reflectance on Sun Damage and Ingredient Efficacy Measurements
Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.
Method/Process
Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer
Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.
Method/Process
Clinical Evaluation of a Zinc- and Copper-based Eye Area Anti-aging Complex
A zinc and copper complex generating biomimetic electricity on a physiological level is shown here to improve the signs of photoaging in preclinical and clinical studies. This complex was applied to the eye area to confirm its efficacy as an anti-aging treatment option with good skin tolerance.
Method/Process
Kao and Tsukuba Univ. Scientists Devise Technique to Visualize the Depths of Skin Wrinkling
Joint research from Kao Corp. and Tsukuba University aims to uncover the depths of structural changes in skin related to wrinkling utilizing an imaging technique that algorithmically localizes backscattered light from skin into layers.
Method/Process
Comparison of Age Determination by Three Evaluation Methods: Self-assessment, Expert Grader and Naïve Grader
This exploratory study investigates how consumers perceive age, using objective and subjective approaches. Results of this study suggest that when a subjective approach is implemented for age determination, subjects affix their emotions to the evaluation. The reverse logic was applicable for the expert and naïve grader methods, as grader results appeared more neutral than the self-assessment.
Method/Process
Using In vivo and In vitro Testing for Evidence-based Development of Anti-aging Ingredients
The need for a conceptual approach to skin aging, the need to combine in vitro and in vivo findings and the new direction for cosmetic ingredient manufacturers are discussed here.
Method/Process
BRAIN AG and Mannheim University of Applied Sciences Publish Article on 3D Skin Models
The article provides a comprehensive table comparing available 3D skin models.
Method/Process
Using In vivo and In vitro Testing for Evidence-based Development of Anti-aging Ingredients
The need for a conceptual approach to skin aging, the need to combine in vitro and in vivo findings and the new direction for cosmetic ingredient manufacturers are discussed here.
Method/Process
Comparison of Age Determination by Three Evaluation Methods: Self-assessment, Expert Grader and Naïve Grader
This exploratory study investigates how consumers perceive age, using objective and subjective approaches. Results of this study suggest that when a subjective approach is implemented for age determination, subjects affix their emotions to the evaluation. The reverse logic was applicable for the expert and naïve grader methods, as grader results appeared more neutral than the self-assessment.
Anti-aging/Face
Safe and Strategic: Hyaluronic and Retinoic Acid Derivative Allays Aging and Acne
A hyaluronic acid and retinoic acid derivative were developed to combine their individual anti-acne and anti-aging efficacies. In vitro and in vivo testing, described here, showed the conjugate penetrated skin to exert the desired biological activities—in low concentrations and without irritation.
Method/Process
The Effect of Skin Metabolism on the Absorption of Chemicals
Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.
Method/Process
The Effect of Skin Metabolism on the Absorption of Chemicals
Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.
Method/Process
Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics
Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.
Preservation
Influence of pH on the Preservative Boosting Effect of Chelating Agents
A system based on phenoxyethanol and ethylhexylglycerin (euxyl® PE 9010) from Schülke & Mayr is described here to boost the efficacy of preservatives. To substantiate its efficacy, the effects of the system were checked at pH levels of both 7.0 and 5.0.
Method/Process
Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics
Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.
Preservation
Influence of pH on the Preservative Boosting Effect of Chelating Agents
A system based on phenoxyethanol and ethylhexylglycerin (euxyl® PE 9010) from Schülke & Mayr is described here to boost the efficacy of preservatives. To substantiate its efficacy, the effects of the system were checked at pH levels of both 7.0 and 5.0.
Method/Process
Collagens I and III, and Elastin Activation for Anti-aging
As an alternative to semi-invasive facial rejuvenation techniques, the authors developed an active ingredient to reactivate senescent fibroblasts by stimulating metabolic pathways for collagens I and III, and elastin. The biological activity of the resulting ingredient is investigated here using in vitro models, ex vivo explants and human volunteers.
Companies
Nature
and Estée Lauder to Honor Up-and-coming Female Researchers
In a new partnership, Nature Research, publisher of the industry-renowned journal
Nature
, and multinational cosmetics giant The Estée Lauder Companies will present early-career female scientists with awards for innovating and inspiring science.
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