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26 Results
Section: Testing > Method/Process
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Event Coverage
Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!
Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.
Method/Process
Moisturizer Penetration in Skin Revealed via Low-coherence Inferometry
Research published in the Russian journal
Engineering
describes a method to measure the penetration of gel moisturizers in skin in vivo via low-coherence interferometry.
SPF/Sun
[podcast] Sunscreen Innovation Act Update: MUsT Test and Penetration Potential
"What’s changed with respect to sunscreen evaluation is ... the test model they are using now is designed for drugs ...and has never been applied previously for the sunscreens," Epstein reports.
Method/Process
Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level: Part II
Part I of this Dermatologic View column appeared in the January issue of
C&T
magazine and described advanced methods to measure skin penetration such as Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Atomic Absorption Spectrophotometry (AAS). Here, the authors continue this investigation of advanced methods to measure skin penetration.
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Method/Process
Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair
The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.
Method/Process
Fluorescence Laser Scanning Confocal Microscopy to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair
The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.
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