Search Cosmetics & Toiletries

13 Results

Type: Article

Section: Testing > Method/Process

Dermagenetics

The advent of the complete transcribing of the human genome will forever alter our perceptions of skin care, medicine and nutrition. This column is edited by Lawrence A. Rheins, PhD.

Predicting the Percutaneous Penetration of Cosmetic Ingredients

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.

Testing for Penetration of the Skin Barrier

The skin barrier is described, after which tests and case studies illustrate how to show if actives and other ingredients have or have not penetrated the skin barrier.

WomanBWGeneTest850

Don’t Count On Genetics, Sunscreens are the Best Bet

In a podcast with P&G scientists Frauke Neuser, Ph.D. and Rosemarie Osborne, Ph.D., Cosmetics & Toiletries learned about genetic studies in support of the Olay brand, and more. Following is an excerpt.

A Dermatological View—Percutaneous Penetration of Amino Acids

Skin care products containing amino acids often promote the benefits conferred on the skin by these molecules. Natural amino acids found in the skin have been found to improve the health of skin through antioxidation, membrane stabilization and increasing skin’s natural moisturizing factor (NMF).

Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!

Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.

Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level

Healthy and intact skin was formerly considered an impermeable barrier designed to shield the living organism from all types of environmental injury, and certainly offering protection from all things chemical. Now skin is recognized as a semi-permeable membrane. Microorganisms cannot penetrate it, but it is pervious to chemicals, selectively allowing molecular passage in and out of the skin.

A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations

This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.

Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!

Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.

Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level: Part II

Part I of this Dermatologic View column appeared in the January issue of C&T magazine and described advanced methods to measure skin penetration such as Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Atomic Absorption Spectrophotometry (AAS). Here, the authors continue this investigation of advanced methods to measure skin penetration.

A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations

This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.

Fluorescence Lscm To Assess The Penetration Of Low Molecular Protein Hydrolyzates Into Hair

Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

Fluorescence Laser Scanning Confocal Microscopy to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

Page 1 of 1