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IBN Engineers Hair Follicle Model for Development of Anti-hair loss Actives

The Institute of Bioengineering and Nanotechnology (IBN) has recently engineered a new hair follicle model that could help discover new drugs or active ingredients for hair regeneration.

Anti-wrinkle Claims Substantiation

Personal care is now dominated by want rather than need, and one facet at the crux of this trend is the taboo word of the century: wrinkles. As with the majority of cosmetic products and claims in the 21st century, product development teams aim to differentiate their products from competitors in one way or another, to create a successful brand and generate profit.

Influence of Pressure During Spreading on UV Transmission Results

This work evaluates the impact of applied pressure during sample spreading on the in vitro measurement of UV transmission. The authors work in a range of pressures between 50–200 g and demonstrate that pressure control is a key parameter that should be strictly controlled to ensure the reliability of test results.

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Influence of Pressure During Spreading on UV Transmission Results

This work evaluates the impact of applied pressure during sample spreading on the in vitro measurement of UV transmission. The authors work in a range of pressures between 50–200 g and demonstrate that pressure control is a key parameter that should be strictly controlled to ensure the reliability of test results.

Characterization of Multilamellar Vesicles for Cleansing Applications

In the present article, the authors characterize a multilamellar vesicle (MLV) system used in personal care and verify its structure via X-ray scattering, rheology and fluorescence microscopy. This enabled the study of MLV formation to investigate bulk rheology characteristics. The results are presented here as application-relevant properties.

In Vitro Methods to Test Materials for Ozone Protective Capabilities

Many markers can be used to indicate epidermal stress. Therefore, it becomes clear that the skin is also a sensitive target to ozone exposure and one that could greatly benefit from cosmetic or personal care materials designed to protect against ozone.

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Sensitive Skin Syndrome: Methodological Approaches

Manufacturers of topical products perform rigorous testing to assure their products are safe for consumers. Of particular interest is determining whether products will irritate the skin of the approximately 50% of consumers surveyed who consider themselves to have “sensitive” skin. The present article describes three such irritancy tests.

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Measuring the Antioxidant Potential of an Acai Extract

The antioxidant potential of cosmetic materials can be evaluated by several methodologies, including a commercial kit that measures total antioxidant status, as illustrated here with a commercial extract from the fruit of the açaí, a Brazilian palm tree. Applications in antiaging products are suggested.

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C + K Introduces Tewameter with Three Probes for Better Efficiency

Courage + Khazaka has upgraded its well-known TEWL and barrier function measurement device, the Tewameter, with three probe heads for better efficiency.

Narcissus Tazetta and Schizandra Chinensis to Regulate ‘Youth Gene Clusters’—An In vitro Analysis

A blend of Narcissus tazetta bulb and Schizandra chinensis fruit extracts was developed for anti-aging benefits and tested for efficacy on a human skin equivalent. Results indicate it regulates the functions of youth gene clusters by increasing the activities found in younger skin and reducing the activities found in aging skin specific to structure, hydration, cellular proliferation and pigmentation.

In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

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In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics

Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.

Using Ultrasound Scanning to Characterize Colloidal Particles

Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

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Screening Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

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In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

Patent Picks—Diffusion Profiling, Optical Tweezer, Fluorescent Microbe Detection and More

Patent Picks are taken from publicly available sources and cover recent patents issued, or applied for, in the cosmetic and personal care industries and relevant peripheral markets. This edition features methods and processes for analyzing and producing cosmetic products and materials.

Solar Flair

If like me, you’re just daydreaming of the beach, this collection of articles will enlighten you with its focus on sun protection, SPF testing, damage repair and more.