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37 Results
Section: Testing
Skin Care
Reverse Labeling is the Best Consumer Magnet Yet
"The Inkey List" line of premium skin care by Be for Beauty turns product labeling on its head.
Anti-aging/Face
[podcast] P&G Scientists on Personal Genetics and 'Good Agers'
P&G has been busy unraveling genetic mysteries to apply in new product concepts. How? This exclusive interview, with Olay scientists, explains. Listen now!
Literature/Data
ZnO Nanoparticles Penetrate but Only Under These Conditions
Zinc oxide (ZnO) nanoparticles are a major component in sunscreens but their ability to permeate skin has remained undetermined. Recent work in
Applied Biomaterials
identifies the conditions under which they penetrate—notably, not in their nano form as they exist in sunscreens.
Methods/Tools
[podcast] Author Commentary: Epigenetics in Cosmetics, with Paul Lawrence, Ph.D.
Today,
Cosmetics & Toiletries
has a special treat for you. Paul Lawrence, Ph.D., co-author on a new three-part article series, shares insights on the potential for epigenetics in cosmetics—not coincidentally, the topic of the series. Listen now!
Event Coverage
Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!
Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.
Testing
Glowing Review: Monk Fruit Encourages Epigenetic Well Aging
Monk fruit extract can be used in a holistic approach to target mature skin. It improves physical and emotional well-being by balancing the skin's epigenetic signature to achieve homeostasis. In this article, the effects of a monk fruit extract are tested on dermal structure, hyaluronic acid and skin radiance. Artificial intelligence also is used to assess its emotional impact on the quality of life in mature women.
Literature/Data
Massive Study Identifies Genetic Indicators for Skin Cancer Risk
The results of a massive study examining some 7,404 cases of squamous cell carcinoma in skin identified genetic associations with this disease, some for the first time.
Methods/Tools
Do Nanomaterials Penetrate Skin? EUON Commissions Review Study
The EUON commissioned a literature review to explore the potential dermal absorption of nanomaterials. Results found the materials rarely penetrate intact skin, except for ionic silver, but a more standardized approach to testing is needed.
Method/Process
Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level
Healthy and intact skin was formerly considered an impermeable barrier designed to shield the living organism from all types of environmental injury, and certainly offering protection from all things chemical. Now skin is recognized as a semi-permeable membrane. Microorganisms cannot penetrate it, but it is pervious to chemicals, selectively allowing molecular passage in and out of the skin.
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Event Coverage
Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!
Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.
Safety/Stability
Research Reviews Non-penetrating Sunscreen Vehicles, Looks to Jojoba
Several "carriers for the future" were highlighted, such as lipid carriers, cyclodextrin derivatives, encapsulation approaches and non-penetrating sunscreens incorporating UV filters and jojoba oil conjugates.
Method/Process
Moisturizer Penetration in Skin Revealed via Low-coherence Inferometry
Research published in the Russian journal
Engineering
describes a method to measure the penetration of gel moisturizers in skin in vivo via low-coherence interferometry.
SPF/Sun
[podcast] Sunscreen Innovation Act Update: MUsT Test and Penetration Potential
"What’s changed with respect to sunscreen evaluation is ... the test model they are using now is designed for drugs ...and has never been applied previously for the sunscreens," Epstein reports.
Method/Process
Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level: Part II
Part I of this Dermatologic View column appeared in the January issue of
C&T
magazine and described advanced methods to measure skin penetration such as Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Atomic Absorption Spectrophotometry (AAS). Here, the authors continue this investigation of advanced methods to measure skin penetration.
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Method/Process
Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair
The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.
Animal Alternatives
Global Experts Outline Next-gen, Animal-alternative Cosmetic Test Tenets
With animal testing for the safety assessment of cosmetic ingredients and products banned in the EU, new methods are required to ensure human safety. As such, an international working group has compiled nine guiding principles to lead the development of new test methods.
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