Heat shock proteins (HSPs) are functional proteins ubiquitously expressed in all organisms. Their expression is induced by elevated temperatures and other external stress factors.1 Research has shown that HSPs have several functions; for example, their expression protects cells from stress-induced damage.2 HSPs also act as molecular chaperones that bind to newly formed proteins to mediate their folding into the correct shape, ensuring proper functioning. In addition, they function in transport activities, interact with other molecules1 and mediate cellular apoptosis.3 Since HSPs play a significant role in regulating the processes associated with cellular protection and repair, they are an important target for topical ingredients that address skin aging, repair and/or protection from damaging conditions.
