Peptide and Protein Combo to Boost Collagen

Lipotec S.A. has introduced a combination of active peptides and proteins that provides a collagen restoring treatment in youth and mature skins. Trylagen (INCI: Water (aqua) (and) pseudoalteromonas ferment extract (and) hydrolyzed wheat protein (and) hydrolyzed soy protein (and) tripeptide-10 citrulline (and) tripeptide-1 (and) lecithin (and) xanthan gum (and) carbomer (and) triethanolamine) is said to provides three functions:

1) Boosts Collagen Synthesis 
During aging, the synthesis of collagen gradually declines. The active ingredients in the product boost the synthesis of collagen types I, III and IV, helping to compensate for decreased  collagen production associated with aging.

2) Organizes Fibril Diameter and Spacing
The process of fibrillogenesis results in the formation of collagen bundles that are responsible for the strength and resilency of the skin. This product reportedly controls collagen fibril dimensions by uniformizing their diameter and spacing them regularly. This provides a better cohesion and stabilization of collagen fibres and gives suppleness to the skin.

3) Inhibits Enzymatic Destruction
After a certain age the degradation of collagen speeds up, due to an increase in MMP (matrix metalloproteinases) levels. Collagenases, a specific type of MMP, cleave fibrillar collagen into smaller fragments, which are then susceptible to further proteolysis. This peptide and protein combination inhibits the production of human MMP-2 and MMP-3, therefore avoiding excessive collagen damage in aged skin. Its anti-collagenase activity protects collagen from degradation.

In addition to enzymatic degradation, another process that damages collagen is glycation. Glycation is a reaction between proteins and sugars in our skin. Sugars act as a kind of glue that sticks proteins together. When glycation affects collagen fibres, they lose their flexibility and elasticity. This product is also said to inhibit glycation, avoiding the formation of AGEs (advanced glycation end-products), protecting skin from the loss of elasticity. 

According to the company, the combination of active peptides and proteins helps maintain collagen quantity and quality, and this is macroscopically translated in a anti-wrinkle effect. For more information, visit

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