Patch Testing vs. In Vitro Alternatives

May 6, 2003 | Contact Author | By: Barrie Drewitt-Barlow, Laura Marshall, and J. McPherson, Hill-Top Research
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Keywords: testing | patch | in vitro | neutral red uptake | validation

Abstract: A comparison between results of in vitro and in vivo testing on a selection of personal-care products begins to establish a validation database for in vitro product safety testing.

The race to get newly formulated products through R&D and on the market shelves has long been the cause of many problems for formulators and marketing departments alike. Occasionaly, products going through months of extensive, costly and time-consuming internal research are only discovered not to meetin acceptability standards when tested by external R&D institutes.

We are all aware of the current European legislation on cosmetic testing using animals and the view of consumers demanding products that have not been tested on animals.