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Testing
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Feb 26, 2010 | 04:56 PM CST
Mechanisms of Tape Stripping and Protein Quantification
By: Ali Alikhan, MD, and Howard I. Maibach, MD
In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.
Feb 26, 2010 | 11:56 AM CST
Microfluidic Testing for LLNA Replacement
By: Katie Schaefer, Cosmetics & Toiletries magazin…
The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.
Feb 26, 2010 | 11:51 AM CST
Translating Data into Claims and Interpreting Regulations: Science vs. Marketing
By: Nava Dayan, PhD, Lipo Chemicals
Substantial evidence, which the FDA requires to support claims for drugs, is applicable to personal care, especially considering the pharmaceutical direction products have taken. The present article considers whether the industry is benefiting from marketing without assuming the responsibility for potential effects. In addition, it considers the limitations of in vitro and in vivo test models.
Jan 29, 2010 | 03:48 PM CST
A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity*
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.
Jan 22, 2010 | 02:47 PM CST
Researchers Mimic the Lymphatic System in Animal Alternative Chip
A chip created by L'Oréal and Hurel Corp. is designed to replace the local lymph node assay, a test often performed on cosmetic raw materials. In addition to saving animals, the chip is also said to be less expensive than animal testing. Hurel developed the working microfluidic portion of the chip.
Jan 21, 2010 | 04:02 PM CST
Strong, Self-healing Hydrogel Created for Tissue Engineering
Researchers from the University of Tokyo have created a strong, self-healing hydrogel with applications in tissue engineering and drug delivery. The material incorporates a binder made from long chains of polyethylene glycol, an ingredient commonly used in skin care.
Jan 12, 2010 | 11:49 AM CST
EU Regulatory Update: Recast of the Cosmetics Directive Published
By: Annelie Struessmann, PhD, CONUSBAT
Regulation (EC) No 1223/2009 was published on Dec. 22, 2009 with the intent to simplify rules and procedures related to the marketing of cosmetic products, a need resulting from different implementations of the Cosmetics Directive.
Oct 26, 2009 | 10:11 AM CDT
Updated Modeling and Simulation Platform for Chemists
A new software platform has been designed to improve the efficiency and effectiveness of chemical and materials research to increase research productivity and decrease time-to-innovation.
Oct 20, 2009 | 11:10 AM CDT
Webinar Focused on Cell-based Assays
BD Biosciences is hosting a webinar dedicated to cell-based assays. Elizabeth Abraham, PhD, a research scientist at BD Biosciences, will discuss the applications for the company's BD PureCoat surfaces.
Oct 13, 2009 | 12:25 PM CDT
In the Land of the Blind: Applying a Single-blind Study to Finished Products
By: Johann W. Wiechers, PhD, JW Solutions
Following positive feedback from a previous column on the placebo effect, Wiechers readdresses clinical study design in relation to cosmetic claim substantiation—this time discussing when to perform double-blind studies and when to perform single-blind studies.