How Dissolving HA Microneedles Change Before/After Application

Sep 29th, 2023

Carly Musleh and Kalliopi Dodou, University of Sunderland, UK

Transdermal microneedle patches enable active ingredients to bypass the slow diffusional process across the stratum corneum’s barrier to reach directly into the deeper skin layers.

Transdermal microneedle patches enable active ingredients to bypass the slow diffusional process across the stratum corneum’s barrier to reach directly into the deeper skin layers.

Transdermal drug delivery involves the passive diffusion of a drug into the systemic circulation via the stratum corneum. It is an appealing alternative to oral drug delivery due to better patient compliance and the avoidance of first pass metabolism. However, it is limited to active ingredients with specific physicochemical properties.^{1, 2}

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Like other markets, efficacy testing, including for cosmetics, is projected to have a substantial increase in revenue by 2027, largely due to pharmaceuticals and biotechnology making constant advancements in relation to public views and the pandemic.

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