Recent in Testing (page 26 of 32)

Ex Vivo Porcine Developed as Alternative to Animal Testing

Symrise and Cutech Srl have developed a new skin model out of pig skin as an alternative to animal testing.

Alternative Testing or Testing Alternatives?

Johann Wiechers, PhD, writes: I am driving in a taxi somewhere with a female colleague when she asks me an intriguing question. “Tell me, Johann, how would you measure breast firming?”

Compass: Direct Routes

Will a flourishing category ever chance revealing this truth behind naturals to consumers? Perhaps so, as the naturals market becomes more saturated and key manufacturers seek ways to drive consumer interest into new areas.

Using Consumers’ Sensory Experience to Achieve Strategic Market Segmentation

Used in conjunction with marketing and marketing research techniques, consumer-based sensory evaluation techniques provide an effective business strategy for product development and brand management.

Computer-aided Formulating

Informatics techniques have been developed that are capable of manipulating huge data sets that underpin modern formulation—from mining for information, to analyzing vast amounts of data. This article highlights how the use of computer technology can increase the efficiency and efficacy of formulating.

Dihydroavenanthramide D for Anti-irritant and Anti-itch

Naturally occurring and synthetic avenanthramides were evaluated for their efficacy to inhibit substance P-induced release of histamine from mast cells. In vivo tests showed that four synthetic avenanthramides demonstrated ability to significantly reduce histamine-induced itch and redness. Dihydroavenanthramide D was also shown to be an excellent antioxidant.

With the Speed of Light: A Look at Accelerated Testing

We test a number of things in our cosmetic industry. We test for safety; for stability; for efficacy; for microbiological contamination; and for interactions between the (ingredients of the) product and its container.

In Vitro and In Vivo Offered for Sunscreen Testing

Laboratoire Dermscan and HelioScreen Labs are combining their skills to offer a complete new in vitro / in vivo service in the field of sunscreen testing.

Preservative Efficacy Testing: Accelerating the Process

A preservative efficacy testing method, called accelerated double challenge, rapidly—in 14 days—assesses the ability of a product or material to resist microbial contamination. It also maintains a high degree of correlation with longer-term preservative challenge protocols.

A Dermatological View—Squamometry: An Early Predictor of Changes in the Skin Barrier

Squamometry is useful in identifying the low or subclinical irritation potential of substances even before any change in the TEWL can be measured.

Testing Tactics: In Vitro Approaches to Antiaging Testing

Using proper methods, it is possible to screen materials for potential antiaging effects; in turn, these materials can be incorporated into cosmetic or personal care products. To properly screen antiaging materials, all that is required is a basic understanding of the aging process.

Modeling UVB-induced Formation of Photoproducts in Human Keratinocytes

The authors describe a model to visualize the appearance of cyclobutane-pyrimidine dimers in the nuclei of normal human keratinocytes after UV irradiation. These dimers are one of the principal agents in DNA damage. The model can be used to assess the effect of a cosmetic ingredient on the formation of direct UV-induced lesions to DNA.

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