ct

Recent in Testing (page 2 of 27)

Recycled Skin: A U.S.-bound, Animal-alternative Test Substrate

Unlike animal, bioprinted or lab-grown skin, real, live human skin that is viably maintained can more realistically provide data on the toxicity and efficacy of drugs and compounds of interest. This is the focus of U.S. biotech newcomer Genoskin.

New Ideas on Hair Breakage: Mending Existing Flaws

Our historical beliefs as to the causes of hair breakage have been largely shaped by findings from testing approaches. More recently, an alternate mechanical testing technique, fatigue testing, has been changing our perspective on this topic.

Antidote for Aging: Synthetic Viper Venom Smooths Over a Cross-cultural Concern

DABBA is a synthetic peptide that mimics Waglerin-1, a toxin from the temple viper. It is shown here to reversibly inhibit muscular contraction and reduce wrinkle formation, and to induce the expression of genes that improve collagen fiber maturation. Notably, differences in anti-wrinkle effects were observed in different ethnicities.

Tox Testing at the Speed of Light (Really)

Until now, testing chemicals for their toxicity has relied on reporter genes, which can take 24 hr to deliver results. A new approach from North Carolina State University, however, uses a modified protein that emits light when binding occurs—effectively signaling its safety.

Is This the Tail End of Animal Testing for Cosmetics and Personal Care?

With awareness of animal testing rising--due in part to conversations via social media and an influx of companies granting "cruelty-free" wishes--brands that are slow to omit animal testing may see consumers opting for other products they know have never been tested on animals.

[podcast] Senescence to Understand Aging in Hair

Aging is a common denominator across not just cultures but substrates. Here, Alison Pawlus, Ph.D., of Aveda, describes a test based on cell senescence to measure the effects of aging in hair and identify ways to mitigate them. Listen now!

Truth in Exposure: Disparity Dictates Product Safety

How often do you relax your hair? or color it? Clearly, some consumers are exposed to given products more than others based on preferences or practices. A new study points to this fact as a crucial component for regulators to consider when determining ingredient safety.

Tomatoes Linked to Decreased Skin Cancer Risk

Tomatoes may be the future of skin cancer prevention, according to new research in Scientific Reports. A study found that the carotenoids in tomatoes have the potential to protect against UV light.

[podcast] Half Megapixel Limit: A Wider Angle Will Enable Better Microbiome Care

"Tools for sampling and sequencing continue to advance," says Larry Weiss, M.D., AOBiome. "16S is the basis for which we look at phylogenies ... [but] do you remember when your phone had like a half a megapixel camera? That’s sort of where we are today."

How Damaged is Hair? Part III: Better Defining the Problem

By identifying elements at the heart of technical issues in hair, product developers will uncover options to consider for improving its health and appearance. Completing our three-part series, this final piece on hair damage provides insight on new ideas and strategies for problematic hair.

When the Dust Settles: Keratinocyte Differentiation is the Anti-pollution Solution

This article describes in vitro, ex vivo and in vivo models to examine the effects of PM in skin, with particular interest in a botanical extract to mitigate the described effects. Urban pollution including particulate matter (PM) can affect the skin barrier by inducing numerous cell stresses.

Australia to Ban Animal Testing on Cosmetics

The bills that will dictate regulatory framework are currently before parliament.

Can't find what you're looking for? Try searching, or looking through past issues.