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New in Function (page 5 of 53)
Feb 01, 2013 | 02:58 PM CST
By: Alain Mavon, PhD, and Carine Jacques-Jamin, Ph…
Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.
Feb 01, 2013 | 02:54 PM CST
By: Ada Polla, Alchimie Forever
The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.
Feb 01, 2013 | 02:43 PM CST
By: Steven Abbott, PhD, Steven Abbott TCNF Ltd. an…
Formulations contain many ingredients that are vital for some important function, such as providing stability. However, what does this “stuff” do in terms of helping or (usually) hindering the delivery of the all-important active? And how much of the active is actually available to deliver? A few simple questions and measurements, described here, can provide a wealth of insight.
Feb 01, 2013 | 02:38 PM CST
By: Jeffery R. Seidling; Scott W. Wenzel; Corey C…
Frequent and repetitive tissue use can lead to inflammation of the nasal area. While technologies were already marketed to help minimize and prevent further irritation, none had targeted the heat and redness associated with an already inflamed nose. This presented a market need but several formulating challenges. Described here are the steps taken to find a practical solution to these challenges.
Feb 01, 2013 | 02:28 PM CST
By: Luigi Rigano, PhD, Studio Rigano Industrial Co…
BB stands for “blemish balm” in Asia or “beauty balm” in some parts of Europe. It is defined loosely as a product that combines serum, moisturizer, base cream, foundation and sunscreen in one.
Jan 04, 2013 | 10:04 AM CST
By: Caroline Mabille, PhD, Rhodia Aubervilliers R…
To maximize perfume delivery from structured cleansing formulations, the fragrance must be introduced before structuring the formulation into multilamellar vesicles. Structured formulations fragranced in such a way are shown here to improve perfume deposition and duration versus micellar systems, with no negative impact on perfume burst during use.
Jan 04, 2013 | 10:00 AM CST
Bar Soap Containing Water-soluble Phosphate Polymers for Controlled Release of Antimicrobial Silver and Other Bioactive Metal Ions
By: David M. Healy, Giltech Ltd.
This paper presents data on the antimicrobial performance of a silver ion-releasing phosphate polymer incorporated into a bar soap product. Two studies test the speed, efficacy and longevity of the antimicrobial effect, highlighting the potential of these materials for the controlled, sustained release of bioactive metal ions in cosmetic products.
Dec 04, 2012 | 11:45 AM CST
By: Marie Ollagnier; Gordon Hsu, PhD; Bryan Moran;…
Skin care formulations often are enriched with high levels of electrolytic ingredients for various skin benefits. However, these have a negative impact on the viscosity, texture and stability of a system. Described in this article is a multifunctional polymer that is designed to provide excellent electrolyte resistance along with a pleasant sensory profile, as will be shown.
Dec 04, 2012 | 11:40 AM CST
By: L. Bergeron; K. Cucumel, PhD; Y. Guerif; L. Mu…
Oxidative stress is a major factor in skin aging, thus a topical compound was designed to increase anti-oxidant coenzyme Q10 (CoQ10) within the body. Described here are in vivo and in vitro studies assessing the compound’s antioxidant and anti-aging capabilities. Results indicate that the modulation of intracellular CoQ10 and its binding proteins appears to protect skin from oxidative damage.
Dec 04, 2012 | 11:30 AM CST
By: Art Georgalas, Georgalas Endeavors
This column proposes that the current natural and organic hair conditioner market can de divided into two types—those that are effective but use technology considered suspect under most natural certifications, i.e., “greenwashed,” and those that are more compliant with natural and organic certification but are found by consumers to have performance gaps