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Section: Cosmetic Ingredients > Actives

Researchers from Newcastle University, the Wellcome Sanger Institute and Kings College London have discovered developmental origins of eczema and psoriasis, leading to possible treatment and new research possibilities for other inflammatory diseases.

Scientists Discover Origins of Eczema and Psoriasis

Research from Newcastle University, the Wellcome Sanger Institute and Kings College London has uncovered the developmental origins of eczema and psoriasis, leading to new possibilities for treatment and means to research other inflammatory conditions.

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Anticellulite Combo of Coriander and Sweet Orange

Silab has combined the fruits of coriander and sweet orange in a cosmetic ingredient to reduce hard cellulite.

The Photostability and Photostabilization of trans-Resveratrol

In this study, the effects of ultraviolet radiation (UVR) on trans-resveratrol were documented, finding that UV radiation causes it to undergo rapid and extensive photoisomerization and some photodecomposition. The antioxidant activity of trans-resveratrol is correspondingly reduced. However, in the presence of ethylhexyl methoxycrylene, a photostabilizer used in sunscreens, the effects of UV exposure on trans-resveratrol are minimized, thereby preserving its antioxidant activity and, presumably, its bioavailability.

The Photostability and Photostabilization of trans-Resveratrol

In this study, the effects of ultraviolet radiation (UVR) on trans-resveratrol were documented, finding that UV radiation causes it to undergo rapid and extensive photoisomerization and some photodecomposition. The antioxidant activity of trans-resveratrol is correspondingly reduced. However, in the presence of ethylhexyl methoxycrylene, a photostabilizer used in sunscreens, the effects of UV exposure on trans-resveratrol are minimized, thereby preserving its antioxidant activity and, presumably, its bioavailability.

Kaempferol is a flavonoid with health-promoting properties found in tea, fruits and vegetables, especially rich in green leafy vegetables such as spinach and kale.

Conagen's Kaempferol Offers Antioxidant and Anti-inflammatory Perks

Conagen’s kaempferol enables brands in nutrition, beauty and personal care products to adopt a more natural position by formulating with clean and sustainable kaempferol.

Penetration And Metabolism Of Isoflavones In Human Skin

This human study shows that the isoflavone aglycone genistein penetrates significantly better into the skin when it is formulated in a liposomal preparation. The corresponding isoflavone glycoside genistin is not hydrolyzed to the biologically active aglycones upon topical application.

Retinoids For Cosmetics

Review and Modern Advances of Retinoids for Cosmetics

For skin cancer, skin aging and acne, retinoids have proven both preventive and therapeutic. Successful efforts toward more bioavailable vitamin A derivatives and retinoid formulations have increased their use for cosmetic benefits. Recent work to further optimize retinoids and reduce their side effects has yielded a new generation of promising molecules, described here.

Lipotec’s Study Offers Cold Weather and Wrinkle Treatment

The Antarcticine marine ingredient is Lipotec’s latest in vivo study, which proved its efficacy to fight cold weather and wrinkles.

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Testing the Fate (and Exposure) of Cosmetic Ingredients

Risk and exposure go hand-in-hand. So when researchers dared to publish a new method to assess the exposure and fate of cosmetic ingredients, we couldn't help but give them exposure, in this review.

Polymers for Thickening and Aesthetics of Surfactant Systems

In the presented study, researchers suggest that acrylates/aminoacrylates/C10-30 alkyl PEG-20 itaconate copolymer serves to stabilize hydroxypropyl starch phosphate polymer in surfactant systems, and also enables hydroxypropyl starch phosphate polymer to further build viscosity.

Penetration of Cosmetics Into and Through the Stratum Corneum

The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.

Antibacterial and Anti-inflammatory Effects of a Magnolia Extract

P. acnes can exacerbate acne as a result of the inflammatory properties of the cell wall short chain fatty acids and chemotactic factors. Here, researchers investigate the effectiveness of a magnolia extract as an acne treatment, based on the known anti-inflammatory and antimicrobial effects from magnolol and honokiol within the material.

Antibacterial and Anti-inflammatory Effects of a Magnolia Extract

P. acnes can exacerbate acne as a result of the inflammatory properties of the cell wall short chain fatty acids and chemotactic factors. Here, researchers investigate the effectiveness of a magnolia extract as an acne treatment, based on the known anti-inflammatory and antimicrobial effects from magnolol and honokiol within the material.

Photostabilization of Retinol and Retinyl Palmitate by Ethylhexyl Methoxycrylene

This study examines the photostability of retinol and retinyl palmitate, finding they break down rapidly when exposed to UV radiation in the 290–400 nm range. This severely reduces their concentrations in finished formulations. However, when combined with ethylhexyl methoxycrylene, these retinoids are shown to be protected against photodegradation, thus preserving their concentrations both during the manufacturing process and following application to the skin.

Penetration of Cosmetics Into and Through the Stratum Corneum

The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.

Consumer Perception of Fine Lines and Wrinkles: Qualitative Assessment

There are varying definitions, associations and overall impressions of fine lines and wrinkles among different consumer segments. The findings of this study offer invaluable insight into consumers’ opinions, and by qualitative in-depth interviews, they provide a well-defined vernacular for aging descriptors. This language is critical for developmental research, consumer evaluation and marketing within the cosmetic industry.

Large-scale Screenings of Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

Report Praises the Skin and Health Benefits of Garlic

In addition to the antifungal, antiaging and skin smoothing benefits of garlic, a study has found the fragrant food to increase antioxidant levels and possibly lower blood pressure and glucose levels.

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