Comparatively Speaking: Dimethicone vs. Methicone

Sep 24th, 2019

Anthony J. O'Lenick, Jr., IFSCC Education Chair

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This column originally appeared on Aug. 5, 2009. It has since been updated to reflect changes in regulations of the cyclics D4, D5 and D6, as well as industry desire to make silicone products that are not only cyclomethicone-free as manufactured, but that cannot hydrolyze into cyclic silicones, either in formulation or in waste treatment gases (so-called biogas). Making methicones instead of dimethicones is one way to accomplish this goal.

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The present study evaluated the efficacy of polysaccharides as prebiotics for the skin microbiome. Hyaluronic acids, carboxymethyl beta-glucan, glucomannan and schizophyllan were tested and changes in Staphylococcus epidermidis and Cutibacterium acnes were measured in vitro and in vivo.

Cosmetic Polysaccharides as Prebiotics for Skin

The present study evaluated the efficacy of polysaccharides as prebiotics for the skin microbiome. Hyaluronic acids, carboxymethyl beta-glucan, glucomannan and schizophyllan were tested & changes in S. epidermidis and C. acnes were measured.

Dreamstime Xl 168719179

Colorescience's All Calm Regimen Neutralizes Redness and Soothes Inflammation

A study published in the Journal of Cosmetic Dermatology found that Colorescience's All Calm Sensitive Skin Regimen was well-tolerated by sensitive skin and improved its visible and physical symptoms.

Investigate Effects of Actives, Raw Materials & Products on the Epigenome

Investigate Effects of Actives, Raw Materials & Products on the Epigenome

Designed to investigate the effects of actives, raw materials and finished products, Genemarkers’ microRNA panel includes 112 markers with a variety of functions related to skin biology. Testing can be performed with in vitro or ex vivo skin tissues.

Pictured: Coffee berry on branch

Coffee Berry Extract Shows Anti-hair Loss, Anti-aging Effects

The presented work is the first report comparing the anti-hair loss and hair growth-promoting effects of caffeine, chlorogenic acid and coffee berry extract in cell-based assays.

The main focus of this research published in the Journal of Cosmetic Dermatology was to define the differences in the hair follicle lipid profiles of female black and gray/white hair follicles.

Research Identifies Age-induced Hair Graying Lipid Biomarkers

Research published in the Journal of Cosmetic Dermatology sought to define differences in the hair follicle lipid profiles of female black and gray/white hair follicles and uncovered age-induced graying biomarkers.

Olumiant is a Janus kinase (JAK) inhibitor, which blocks the activity of one or more of a specific family of enzymes, interfering with the pathway that leads to inflammation, thereby, treating patients with alopecia areata.

FDA Approves First Systemic Alopecia Areata Treatment

Olumiant is a Janus kinase (JAK) inhibitor, which blocks the activity of one or more of a specific family of enzymes, interfering with the pathway that leads to inflammation to thereby treat patients with alopecia areata.

The development of molecules to interact with the nervous system has expanded skin care into neurocosmetics, and this trend has moved into hair and scalp care. This report identifies biological targets for the development of such actives, and their potential to improve hair and scalp care cosmetic products.

Neuro-cosmetic Targets for Scalp and Hair Care

This report identifies biological targets for the development of such actives, and their potential to improve hair and scalp care cosmetic products.

TDF Blu Viole Sunscreen specifically protects the skin from not only sun damage but blue light as well, preventing hyperpigmentation, melasma and brown spots.

TDF Blu Voile Sunscreen Found to Protect Against Blue Light

The skin-protecting efficacy against the effects of blue light irradiation was analyzed, as well as the quantitative and qualitative evaluation of protein carbonylation in human skin explants.

There remains an unmet need for a robust and reliable method to standardize the pollution protection factor measurement of any composition for use as a tool to assess/grade cosmetics based on their efficacy.

Patent Pick: Unilever Standardizes Pollution Protection Factor for Cosmetics

Unilever discloses a method to standardize the measurement of a pollution protection factor (PPF) for cosmetic compositions in a recent European patent.

Findings demonstrate the protective role of S. hominis, a ubiquitous colonizer of human skin, against opportunistic damage and pathogens.

6 Ways Staphylococcus Hominis Protects Skin Through Quorum Sensing

Work published in mBio reveals how the skin commensal Staphylococcus hominis inhibits quorum sensing in six ways to protect against opportunistic pathogens, e.g., Staphylococcus aureus.

The approach could be used to develop eco-friendlier products for hair strengthening and setting.

Green Method Using Blue Light Strengthens, Sets Hair

A paper published in the Journal of Cleaner Production describes the clean, one-step crosslinking of keratin to strengthen and set hair using blue light and eco-friendly chemicals such as citric acid.