Abstract
Medicinal herbs have been used as natural healing and cosmetic remedies since ancient times. The annual flowering plant, Nigella sativa, its black seeds and oil derived from them were used for medicinal and beauty routines since the ancient Egyptian pharaohs and queens. To harness the power of the Nigella sativa (black seed) oil (BSO), its active constituent, thymoquinone, and their demonstrated benefits, a cold-pressed, full-spectrum black seed oil, standardized to 3% thymoquinone and very low FFAs was developed.
Branded as B’utyQuinTM, BSO has been studied to determine action mechanisms related to mitochondrial biogenesis and revitalization. Followed by human clinical research to establish the efficacy of BSO as anti-aging aid. BSO positively impacted several characteristics of aging skin in a placebo-controlled clinical trial. It showed significant improvements in skin hydration, luminosity, firmness, and elasticity, when compared to placebo, resulting in a flawless appearance.
Nigella sativa, black seed oil, thymoquinone, anti-aging, mitochondrial biogenesis, mitochondrial health, skin rejuvenation, B’utyQuin
Introduction
Medicinal herbs have been used as natural healing and cosmetic remedies since ancient times. The annual flowering plant, Nigella sativa (N. sativa, family Ranunculaceae), is native to southeastern Europe, western Asia, the Middle East, and northern Africa. It is also cultivated in various parts of the world for nutritional and cosmetic purposes, traditional medicine, as well as a source of its unique constituents. Oil from the small black seeds of N. sativa, has been used for medicinal and beauty treatments since the days of the Egyptian pharaohs and Cleopatra and is featured in the Bible and Koran as the “curative black cumin.” More recently, black seed oil has been studied for its many health and cosmetic, anti-inflammatory, antioxidant, and anti-aging benefits. Determination of the major chemical components of N. sativa seed, and the key active molecule known as thymoquinone (TQ) has resulted in a growing interest in N. sativa as a therapeutic agent for a variety of conditions.
To harness the incredible power of the active constituent thymoquinone and its demonstrated benefits, TriNutra™, has cultivated a high in TQ N. sativa strain to deliver full-spectrum,
cold-pressed black seed oil standardized to 3% thymoquinone and very low (<2%) free fatty acids, the highest quality and most potent thymoquinone concentration in cold-pressed oil available on the market. TriNutra’s farm-to-finished black seed oil features full sustainability and traceability by completely controlling all steps in one location to guarantee a superior quality material. TriNutra’s cold-pressed black seed oil is branded as B’utyQuin™ for cosmetic use and ThymoQuin® for nutraceuticals.
B’utyQuin’s black seed oil (BSO) is formulated to contain a proprietary, patent-pending composition of constituents with superior potency that act synergistically to maximize the anti-inflammatory, antioxidant, and antimicrobial effects of the oil.
To understand and elucidate the mechanisms of action of B’utyQuin on and inside the skin, both in vitro studies and clinical trials have been conducted to assess this BSO’s role in mitochondrial revitalization and rejuvenation, boosting ATP production, reducing oxidative stress and inflammation, all having protective benefits for aging skin. The clinical trial assessed the efficacy as well as safety and compatibility of a topical cosmetic product containing 3% B’utyQuin in an Anti-Aging Facial Cream (Active Cream), after application under normal conditions of use.
(Figure 1: Mechanism of Action Elucidation Behind B’utyQuin - Black Seed Oil with 3% Thymoquinone.)
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