Recent in In vivo (page 5 of 5)

In Vivo Quantitative Evaluation of Gloss

A real time polarization analysis technique is described that differentiates components of scattered light in video images and enables in vivo quantitative evaluation of gloss from hair and skin during quality control and claims substantiation.

Testing for Penetration of the Skin Barrier

The skin barrier is described, after which tests and case studies illustrate how to show if actives and other ingredients have or have not penetrated the skin barrier.

Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level

Healthy and intact skin was formerly considered an impermeable barrier designed to shield the living organism from all types of environmental injury, and certainly offering protection from all things chemical. Now skin is recognized as a semi-permeable membrane. Microorganisms cannot penetrate it, but it is pervious to chemicals, selectively allowing molecular passage in and out of the skin.

Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level: Part II

Part I of this Dermatologic View column appeared in the January issue of C&T magazine and described advanced methods to measure skin penetration such as Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Atomic Absorption Spectrophotometry (AAS). Here, the authors continue this investigation of advanced methods to measure skin penetration.

Cyclic Testing: Demonstrating Conditioner Benefits on Damaged Hair

Cyclic fatigue testing simulated stresses experienced by hair fibers from repeated grooming and styling. Researchers used the Weibull parameter of characteristic life to assess damage. Survival probability graphs showed conditioner use helped damaged hair.

Cosmetic Testing in 2000 and Beyond

Changes in cosmetic testing are being driven by regulation and advanced technologies, such as new in vitro methods, molecular combinational chemistry and skin delivery. Part of the Series: From Test to Claim.

Measured Dermal Effect of Applying Retin-A

The research reported here focuses on the dermis because it is the site of the primary water retention molecule, hyaluronic acid (HA) in the skin.

Strategies to Reduce Contact Allergy to Fragrances

The author discusses current animal-based testing and proposes a strategy based on maximum permitted levels of certain fragrance ingredients in cosmetics as ways to reduce contact allergy to fragrances in cosmetic products.

Properties of a Pseudoceramide Multi-Lamellar Emulsion In Vitro and In Vivo

Tests of a pseudoceramide multi-lamellar emulsion formulation for its stability and its assistance to barrier recovery in vivo on damaged skin suggest dermatologic and cosmetic possibilities.

Correlating Porosity and Tensile Strength of Chemically Modified Hair

This study validates the porosity method against the widely accepted method of tensile strength for determining the hair damage imparted to hair due to cosmetic treatments.