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In vivo
New in In vivo (page 5 of 6)
Dec 23, 2005 | 05:59 PM CST
Evaluating ACD Frequency After Reducing Exposure to Sensitizers
By: N.O. Wesley and Howard I. Maibach, MD
The economic burden of contact dermatitis is extensive due to work hours lost and physician visits. In the workplace, for example, contact dermatitis (irritant and allergic) accounts for 40% of all occupational illnesses (excluding injury) and 25% of time lost from work. Common sensitizers leading to allergic contact dermatitis (ACD) include metals, plants, cosmetics, rubber compounds and medicines.
Dec 23, 2005 | 05:38 PM CST
Using Skin Models to Assess the Effects of a Skin Care Emulsion on Skin Barrier Function
By: A. zur Muehlen, A. Klotz, M. Veeger, B. Thorne…
This study utilizes a 3D skin model to investigate barrier repair after damage with SDS and application of a skin care emulsion; it also demonstrates the suitability of using 3D skin models to study barrier repair.
Dec 23, 2005 | 03:13 PM CST
In Vivo Quantitative Evaluation of Gloss
By: P. Clémenceau, S. Breugnot and B. Pouet, Bossa…
A real time polarization analysis technique is described that differentiates components of scattered light in video images and enables in vivo quantitative evaluation of gloss from hair and skin during quality control and claims substantiation.
Dec 23, 2005 | 02:27 PM CST
Testing for Penetration of the Skin Barrier
By: Theresa M. Callaghan, Hill Top Research Inc.
The skin barrier is described, after which tests and case studies illustrate how to show if actives and other ingredients have or have not penetrated the skin barrier.
Dec 13, 2005 | 11:28 PM CST
Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level
By: Jurij J. Hostynek and H.I. Maibach
Healthy and intact skin was formerly considered an impermeable barrier designed to shield the living organism from all types of environmental injury, and certainly offering protection from all things chemical. Now skin is recognized as a semi-permeable membrane. Microorganisms cannot penetrate it, but it is pervious to chemicals, selectively allowing molecular passage in and out of the skin.
Dec 13, 2005 | 10:56 PM CST
Advanced Methods Measure Skin Penetrants at the Parts-Per-Billion Level: Part II
By: Jurij J. Hostynek and H.I. Maibach
Part I of this Dermatologic View column appeared in the January issue of C&T magazine and described advanced methods to measure skin penetration such as Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Atomic Absorption Spectrophotometry (AAS). Here, the authors continue this investigation of advanced methods to measure skin penetration.
Dec 31, 2003 | 06:19 PM CST
Cyclic Testing: Demonstrating Conditioner Benefits on Damaged Hair
By: Sidney B. Hornby, Mar-Tech Contract Services I…
Cyclic fatigue testing simulated stresses experienced by hair fibers from repeated grooming and styling. Researchers used the Weibull parameter of characteristic life to assess damage. Survival probability graphs showed conditioner use helped damaged hair.
May 06, 2003 | 02:00 AM CDT
Correlating Porosity and Tensile Strength of Chemically Modified Hair
By: Ali N. Syed and hasan Ayoub, Avlon Industries …
This study validates the porosity method against the widely accepted method of tensile strength for determining the hair damage imparted to hair due to cosmetic treatments.
May 06, 2003 | 02:00 AM CDT
Cosmetic Testing in 2000 and Beyond
By: Johann W. Wiechers, PhD, Uniqema
Changes in cosmetic testing are being driven by regulation and advanced technologies, such as new in vitro methods, molecular combinational chemistry and skin delivery. Part of the Series: From Test to Claim.
May 06, 2003 | 02:00 AM CDT
Measured Dermal Effect of Applying Retin-A
By: George Andrassy and Howard I. Maibach, Univers…
The research reported here focuses on the dermis because it is the site of the primary water retention molecule, hyaluronic acid (HA) in the skin.