In vitro

Zeta Potential and Particle Size to Predict Emulsion Stability

Nov 19, 2014A.P. Gasparelo†, ‡; C. Dal Pizzol†; P. Fernanda Campos de Menezes†; R.V. Knapik†; M.A. Trindade Costa†; M.R. Machado Prado‡; and C.E. de Oliveira Praes†; † Grupo Boticário, São José dos Pinhais, Brazil; and ‡ Faculdades Pequeno Príncipe, Curitiba, Brazil

Emulsions are popular vehicles in skin care due to their affinity for the skin; however, they are thermodynamically unstable systems. This study investigates zeta potential and particle size distribution as potential screening tools to predict instabilities in emulsion-based cosmetic products, to supplement regular accelerated stability testing.

Collagens I and III, and Elastin Activation for Anti-aging

Feb 24, 2014D. Auriol and G. Redziniak Libragen; and H. Chajra, K. Schweikert and F. Lefevre, Induchem

As an alternative to semi-invasive facial rejuvenation techniques, the authors developed an active ingredient to reactivate senescent fibroblasts by stimulating metabolic pathways for collagens I and III, and elastin. The biological activity of the resulting ingredient is investigated here using in vitro models, ex vivo explants and human volunteers.

Measuring the Water Content of Hair

Feb 21, 2014Trefor A Evans, T.A Evans LLC

Consumers have demonstrated a clear desire for hair that isn’t “dried out” while also demonstrating a clear distaste for the effects of high humidity on hair. To find the balance in creating products, it is necessary to have an accurate means of measuring hair’s water content. This article describes equipment used to perform this task while highlighting experimental variables that can produce suspect results and lead to incorrect conclusions.