In vitro

Zeta Potential and Particle Size to Predict Emulsion Stability

Nov 19, 2014A.P. Gasparelo†, ‡; C. Dal Pizzol†; P. Fernanda Campos de Menezes†; R.V. Knapik†; M.A. Trindade Costa†; M.R. Machado Prado‡; and C.E. de Oliveira Praes†; † Grupo Boticário, São José dos Pinhais, Brazil; and ‡ Faculdades Pequeno Príncipe, Curitiba, Brazil

Emulsions are popular vehicles in skin care due to their affinity for the skin; however, they are thermodynamically unstable systems. This study investigates zeta potential and particle size distribution as potential screening tools to predict instabilities in emulsion-based cosmetic products, to supplement regular accelerated stability testing.