Recent in In vitro (page 7 of 11)
Apr 1, 2009 | Hongbo Zhai, MD, University of California; and Howard I. Maibach, MD, University of California School of Medicine
The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.
Feb 27, 2009 | Nava Dayan, PhD, Lipo Chemicals Inc.
Ex vivo skin absorption studies measure the penetration and permeation of a compound to assess its safety, and can assist the formulator in increasing product efficacy and reducing toxicity. This review analyzes the currently available guidelines published by four major regulatory organizations to clarify important milestones in study design, data analysis and interpretation.
Feb 27, 2009
Knight Scientific Ltd. offers a kit to manufacturers to measure the antioxidant capacity of their finished nutraceuticals and cosmetics to justify claims, produce technical documents, confirm batch uniformity and more.
Feb 23, 2009 | Johann W. Wiechers, PhD, JW Solutions
In this column, the author investigates the source of the placebo effect. In addition, he asks the question: Must cosmetics testing always incorporate tests against a placebo?
Jan 30, 2009 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California School of Medicine
The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.
Jan 29, 2009
This first effort is focused on the key performance attributes of shampoos, 2-in-1 shampoo and conditioners and shampoo/conditioner systems.
Dec 19, 2008
The European Centre for the Validation of Alternative Methods' (ECVAM) Scientific Advisory Committee (ESAC) endorsed the scientific validity of two in vitro skin irritation tests at its 29th meeting.
Oct 1, 2008 | Robert Holtz, BioInnovation Laboratories
Many markers can be used to indicate epidermal stress. Therefore, it becomes clear that the skin is also a sensitive target to ozone exposure and one that could greatly benefit from cosmetic or personal care materials designed to protect against ozone.
Sep 24, 2008
Lonza announces the availability of primary Clonetics Adult Normal Human Epidermal Melanocytes.
Aug 29, 2008 | Theresa Callaghan, PhD
It remains the responsibility of the manufacturer to substantiate the safety of both ingredients and finished cosmetic products prior to their being marketed.
Aug 29, 2008 | Miranda Farage, PhD, Procter & Gamble and Howard Maibach, University of California School of Medicine
Manufacturers of topical products perform rigorous testing to assure that their products are safe for consumers. Of particular interest is determining whether products will irritate the skin of the approximately 50% of consumers surveyed who consider themselves to have “sensitive” skin.
Aug 18, 2008
The ACS announced at its 236th meeting that it has carried out a microscopic analysis of hair fibers interacting with each other. The researchers find that this information will be beneficial to cosmetic chemists who formulate hair repair products.