In vitro

Recent in In vitro (page 3 of 11)

Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics

The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.

DNA: Hard Evidence of Cosmeceutical Claims

To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.

In Vitro Model for Decontamination of Human Skin

The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.

Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

Assessing the Impact of Hair Damage Types on Color Retention

This article reviews and assesses damage types caused to hair before and after artificial coloration, i.e., by bleaching, perming, heat treatment, UV exposure and shampooing, to compare how they impact color durability individually and combined. Formulation emerges as the key to designing shampoos that efficiently deliver actives to improve color protection against these and other damage types.

Assessing the Impact of Hair Damage Types on Color Retention

This article reviews and assesses damage types caused to hair before and after artificial coloration, i.e., by bleaching, perming, heat treatment, UV exposure and shampooing, to compare how they impact color durability individually and combined. Formulation emerges as the key to designing shampoos that efficiently deliver actives to improve color protection against these and other damage types.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

Hair Color Vibrance Factor to Characterize Shine and Color Intensity*

To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.

Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry

Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.

Testing Tactics—Consumer vs. Scientific Language: Relating In vivo to In vitro

It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.

Evaluating Essential Oils in Cosmetics: Antioxidant Capacity and Functionality

In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.

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