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New in In vitro (page 3 of 15)
Mar 05, 2013 | 12:21 PM CST
By: Olga V. Dueva-Koganov, PhD, Artyom Duev and St…
Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.
Mar 05, 2013 | 11:49 AM CST
By: S. Miksa, D. Lutz and J. Ongenaed, HelioScreen…
This work evaluates the impact of a plasma treatment on test substrates to modify their surface energy, to more closely correlate in vitro SPF measurements with in vivo measurements—without chemically altering the test products. The authors chose the level of plasma modification to use on a substrate based on in vivo values; they explain how to choose it regarding specific formulas in a further paper.
Feb 01, 2013 | 02:58 PM CST
By: Alain Mavon, PhD, and Carine Jacques-Jamin, Ph…
Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.
Nov 20, 2012 | 02:23 PM CST
Pepchipomics is a new project supported by the FP7 of the European Union aimed at synthesizing and reading high-density peptide microarrays, resulting in a new high-throughput platform that integrates peptide synthesis, detection and analysis at an unprecedented scale.
Nov 06, 2012 | 12:12 PM CST
By: Kwangsuk Joo, Ongsoo Kim, Heonsik Kim and Jeu…
This study describes methods used in a Korean study to calculate consumer exposure to lipstick and face creams. The average amount applied daily was estimated and compared with data collected by weighing containers before and after use. The data collected was 1.8 to 1.6 times greater than the estimate, so although the survey represented real use patterns, the actual data was more accurate.
Nov 01, 2012 | 03:53 PM CDT
By: Rachel Grabenhofer
For the current picture, Cosmetics & Toiletries knows many of the headaches you endure; for example, regulations and scale-up. It would take volumes to address all the challenges these pose, but this issue covers two specific aspects of them.
Nov 01, 2012 | 02:47 PM CDT
By: Kathleen A. Martin, PhD, McCrone Associates In…
Particulate contamination and discoloration may occur in products due to foreign materials introduced via raw materials or during the manufacturing process. Agglomeration or reactions between ingredients and packaging components also are possible sources. The identification of contaminants and their origin, described here, is therefore critical so that future incidents can be prevented and safety or regulatory concerns can be addressed.
Oct 24, 2012 | 03:36 PM CDT
By: Rachel L. Grabenhofer
The 2012 IFSCC Congress opened with a frenzy; the "African Frenzy" dancers, that is, and enlightened attendees over three days with 65+ presentations and more than 150 posters.
Oct 23, 2012 | 09:32 AM CDT
Malvern Instuments has launched a device suitable for the characterization of proteins and nanoparticles where the highest sensitivity for size and zeta potential measurement is required.
Oct 03, 2012 | 09:45 AM CDT
The need for a conceptual approach to skin aging, the need to combine in vitro and in vivo findings and the new direction for cosmetic ingredient manufacturers are discussed here.