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Recent in Testing (page 3 of 28)

BASF-Poietis Deal to Take 3D Bioprinting to Cellular Depths

BASF and 3D bioprinting expert Poietis have big plans to advance skin care. In an extended agreement, the two will collaborate to optimize the 3D bioprinting of skin equivalent models to study the effectiveness of actives.

Creme RIFM Model Reveals Aggregate Fragrance Exposure

Good news on the testing front: a model jointly developed by the Research Institute for Fragrance Materials and Creme Global recently showed consumer exposure to fragrances from personal care products tends to be over-estimated.

Are Your Sunscreens Infra-ready? New In vitro Method Puts Data Behind the Claims

Considering more and more sun care products are claiming infrared (IR) protection, it is important to standardize the parameters by which they are evaluated. Since IR-A and IR-B are the most implicated in skin damage, a test method was developed based on these wavelengths, as described here.

Silab’s Whitonyl Witnesses New Data

Silab’s active helps control melanogenesis and its environment, and the company has come up with new data to prove the ingredient's efficacy. This ingredient can be utilized to enhance complexion radiance, with depigmenting and lightening action.

Recycled Skin: A U.S.-bound, Animal-alternative Test Substrate

Unlike animal, bioprinted or lab-grown skin, real, live human skin that is viably maintained can more realistically provide data on the toxicity and efficacy of drugs and compounds of interest. This is the focus of U.S. biotech newcomer Genoskin.

New Ideas on Hair Breakage: Mending Existing Flaws

Our historical beliefs as to the causes of hair breakage have been largely shaped by findings from testing approaches. More recently, an alternate mechanical testing technique, fatigue testing, has been changing our perspective on this topic.

Antidote for Aging: Synthetic Viper Venom Smooths Over a Cross-cultural Concern

DABBA is a synthetic peptide that mimics Waglerin-1, a toxin from the temple viper. It is shown here to reversibly inhibit muscular contraction and reduce wrinkle formation, and to induce the expression of genes that improve collagen fiber maturation. Notably, differences in anti-wrinkle effects were observed in different ethnicities.

Tox Testing at the Speed of Light (Really)

Until now, testing chemicals for their toxicity has relied on reporter genes, which can take 24 hr to deliver results. A new approach from North Carolina State University, however, uses a modified protein that emits light when binding occurs—effectively signaling its safety.

Is This the Tail End of Animal Testing for Cosmetics and Personal Care?

With awareness of animal testing rising--due in part to conversations via social media and an influx of companies granting "cruelty-free" wishes--brands that are slow to omit animal testing may see consumers opting for other products they know have never been tested on animals.

[podcast] Senescence to Understand Aging in Hair

Aging is a common denominator across not just cultures but substrates. Here, Alison Pawlus, Ph.D., of Aveda, describes a test based on cell senescence to measure the effects of aging in hair and identify ways to mitigate them. Listen now!

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